Gram (-) Rods/Bacilli Flashcards

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1
Q
aerobe (non-fermenting)
oxidase +
catalase +
pyocyanin, fruit like odor
capsule, exotoxin, endotoxin
ubiquitously found in H20
A

P. aeruginosa

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2
Q
burn patients
hot tub folliculitis
Cystic fibrosis pts at risk
Ecthyma gangrosum (black center, erythematous margin)
chronic granulomatous disease
A

P. aeruginosa

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3
Q

because infxn w/ P. aeruginosa looks similar to enteric bacterial infxn, what is used to distinguish?

A

oxidase test
P. aeruginosa is oxidase +
enteric bacteria are oxidase -

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4
Q

mechanism of action of exotoxin of P. aeruginosa

A

inhibits protein synthesis vis eEF-2

similar to diptheria

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5
Q

transmission via aerosol droplets from contaminated air conditioning system

A

Legionella pneumophila

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6
Q
weakly gram (-)
charcoal yeast extract agar (cysteine & iron)
silver stain +
facultative intracellular
A

Legionella pneumophilia

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7
Q

pontiac fever is cause by what bacteria

A

Legionella pneumophilia

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8
Q

Legionnaires disease is seem in what population of pts

A

smokers/drinkers/ >55 years/ immunocompromised

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9
Q

dx of legeionella

A

direct fluorescent antibody
no gram stain bc it stains weak
4x increase in ab

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10
Q

tx of legionella

A

abx that penetrates human cells
floroquinolones, erythromycin, azithromycin
add rifampin if immunocompromised

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11
Q
Gram - rod
facultative intracellular
zoonotic
potential biowarfare
tick bite --> rabbit---> human
A

Fancisella tularensis

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12
Q
gram - rod
aerobe
capsule 
reservoir- vaccinated human
Mucosal surface pathogen
Regan-Lowe media
VACCINE
A

Bordetella pertussis

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13
Q

MOA pertussis toxin

A

ribosylation of Gi–> inc. AC–> inc. cAMP

hypoglycemia
block immune effector cells
increase histamine sensitivity

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14
Q

best stage to culture pertussis

A

catarrhal stage

“Cold” like illness

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15
Q

stage whooping cough shows up

A

paroxysmal stage

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16
Q
gram -
aerobic
zoonotic 
faculative intracellular
biowarfare
cattle/unpasteurized dairy products
Undulant fever, profuse sweating
A

Brucella

abortus (cattle), melitensis (goat), suis (pig)

17
Q
gram - curved rod w/ polar flagella 
"gulls wings"
oxidase +
Microaerophilic, 42C growth
POULTRY, fecal oral 
low infectious dose
invades mucosa--> blood diarrhea
most common infectious gastroenteritis
A

Camplobacter jejuni

18
Q

serious complication of C. jejuni infxn

A

guillane barre syndrome