Gram (-) Cocci

Question 1

gram (-)
diplocicci- kidney bean shaped
oxidase +
glucose fermenters
grow on thayer martin agar

Answer 1

Neisseria

Question 2

gram (-)
diplocicco/kidney bean shaped
nasopharynx--> respiratory droplets
oxidase +
glucose fermenter
maltose fermenter
chocolate agar
Vaccine (does not cover Type B capsule)

Answer 2

N. meningitidis

Question 3

most important virulence factor in N. meningitidis

Answer 3

polysaccharide capsule

Question 4

deficiency in what complements components predisposes you to bacteremia from N. meningitidis?

Answer 4

C5-9 (late complement components)

If see a person with N. meningitidis infxn who had vaccine think they have this deficiency

Question 5

Abrupt onset w/ fever, chills, stiff neck, vomitting

Answer 5

N. meningitidis meningitis

Question 6

Seen in late infxn w/ N. meningitidis

Answer 6

rash that is petechial
due to bacteremia

Waterhouse-Friderichsen Syndrome- often children- collaped adrenal glands–> rapidly fatal

Question 7

gram (-)
Intracellular
No capsule
Thayer martin agar
oxidase +
ferments glucose
Does not ferment maltose
Pili- attachment, inhibit phagocytic uptake, antigenic variation
Organism invades mucosal surfaces--> inflammation

Answer 7

N. gonorrheae

Question 8

men- urethritis (purulent discharge-white- PMNs)
women- often asymptomatic (PID)
Infants- opthalmia—> blindness

Answer 8

N. gonorrheae

Question 9

Moraxella catarrhalis

Answer 9

Normal URT flora
respiratory droplets
sinusitis, otitis media
more serious disease in elderly/underlying lung disease
Rx resistance (B-lactamase)- amoxicillin + clavulanate, TMP-SMX