GORD Flashcards

1
Q

What does GORD stand for?

A

Gastro-oesophageal reflux disease

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2
Q

What are some things that can cause GORD?

A

Hiatus hernia, smoking, alcohol, obesity, pregnancy

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3
Q

What oesophageal signs/symptoms might a patient experience?

A

Heartburn, belching, odynophagia

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4
Q

What is odynophagia?

A

Painful swallowing

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5
Q

What extra-oesophageal signs/symptoms might a patient experience?

A

Nocturnal asthma, chronic cough, laryngitis, sinusitis

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6
Q

What investigations can you do?

A

Endoscopy if red flags

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7
Q

What are some alarm symptoms?

A

Dysphagia, >55, weight loss, epigastric pain, treatment resistant dyspepsia, nausea and vomiting, anaemia, raised platelets

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8
Q

What could GORD be confused with?

A

Angina

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9
Q

What lifestyle changes would you advise?

A

Wt loss, smoking cessation, avoid alcohol, raise head when sleeping

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10
Q

What foods/drinks should people with GORD avoid?

A

Hot drinks, alcohol, citrus fruits, tomatoes, onions, fizzy, spice, caffeine, chocolate

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11
Q

What drugs can you prescribe?

A

PPI, H2 receptor antagonist

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12
Q

What is the aim of surgical treatment?

A

Increase resting lower oesophageal sphincter

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13
Q

What is the surgical operation to treat GORD?

A

Nissen fundoplication, fundus is wrapped around lower oesophagus

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14
Q

What are complications of GORD?

A

Barrett’s oesophagus, oesophagitis, oesophageal ulcers or strictures

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15
Q

What metaplasia occurs in Barrett’s oesophagus?

A

Stratified squamous epithelial cells change into simple columnar

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16
Q

What is a complication of Barrett’s oesophagus?

A

Progression to oesophageal cancer

17
Q

What is GORD heartburn characterised by?

A

Worse after meals and when lying, relieved by antacids

18
Q

Give 2 examples of PPIs

A

Lansoprazole, Omeprazole

19
Q

What do parietal cells do?

A

Produce intrinsic factor and HCl

20
Q

Give an example of a H2 antagonist

A

Ranitidine

21
Q

What is achalasia?

A

When lower oesophageal sphincter doesn’t open