GOG249, 2020

Question 1

Study question for GOG249, 2019?

Answer 1

Does VBT + chemo incr RFS vs pelvic RT?

Question 2

Study design of GOG249?

Answer 2

VBT f/b IV taxol and carbo q 3 weeks (3 cycles); pelvic RT over 5 weeks (45-50 Gy); RCT; RFS

Question 3

Inclusion criteria GOG 249?

Answer 3

Stage 1 endometrioid HIR, Stage 2 or Stage 1-2 serous or clear cell; recommended b/l P- and PA- lymphadenectomy

Question 4

Results of GOG249?

Answer 4

No diff of 5y RFS and OS (VBT and chemo not better than Pelvic RT alone)