Gn associated with Infection

Question 1

Risk factors for renal disease associated with endocarditis

Answer 1

1. hemodialysis patient

2. congenital heart disease and cardiac surgery in pediatric patients

Question 2

Most common bacterial etiology of renal disease associated with endocarditis

Answer 2

1. S. aureus

2. S. viridans

Question 3

Which organism is associated with superantigen-induced immune reactivity with noted IgA deposits?

Answer 3

Methicillin-resistant S. aureus

Question 4

Which malarial strain/s produce/s a relatively benign condition with mesangioproliferative glomerulonephritis?

Answer 4

1. P. vivax

2. P. ovale

Question 5

What are the expected biopsy findings in Hepatitis C-associated glomerulonephritis?

Answer 5

1. cryoglobulinemic GN
2. MGN
3. Type 1 MPGN

Question 6

Which two drugs, when taken together for recreational purposes, can produce a nephropathy presenting as nephrotic syndrome and Focal Sclerosing Glomerulosclerosis on biopsy?

Answer 6

1. Pentazocine

2. Tripelennamine

Question 7

What is the hallmark of NSAID-induced nephropathy?

Answer 7

1. acute interstitial nephritis

2. nephrotic syndrome

Question 8

Clinical features of renal disease associated with Infective endocarditis

Answer 8

1. Osler’s nodes, Janeway lesions, splinter hemorrhages
2. Fever withor without arthralgia, leukocytosis, elevated ESR, purpura
3. Mild asymptomatic urinary abnormalities (hematuria, pyuria, albuminuria)
4. hypocomplementemia
5. Renal insufficiency

Question 9

Which pathogen produces Membranous GN in children and MPGN in adults with biospy findings of renal artery aneurysms, renal infarctions, and ischemic scarring?

Answer 9

Hepatitis B

Question 10

Condition causing deposition of immune complexes, or in situ formation of immune complexes in kidney parenchyma

Answer 10

HIVICK (HIV Immune Complex Kidney Disease)

Question 11

Condition wherein renal epithelial cells replicate virus and host immune response

Answer 11

HIVAN (HIV-Associated Nephropathy)

Question 12

HIVICK histopath presentation

Answer 12

1. IgA nephropathy
2. Membranous/MPGN
3. lupus-like glomerulonephritis

Question 13

HIVAN histopath presentation

Answer 13

1. FSGS
2. MPGN
3. DPGN
4. IgA Nephropathy
5. MCD

Question 14

Clinical features of shunt nephritis

Answer 14

1. Recurrent episodesof fever, anemia, hepatosplenomegaly, skin rash, elevated ICP symptoms
2. Proteinuria, Hematuria, Hypertension
3. Hypocomplementemia, Anemia, Elevated ESR and rheumatoid factor titers
4. renal biopsy indistinguishable form endocarditis associated nephropathy

Question 15

Carcinomas usually associated with glomerular lesions

Answer 15

1. Lung
2. Stomach
3. Breast
4. Colon

Question 16

Usual clinical presentation of IgA-dominant glomerulonephritis associated with streptococcal infections

Answer 16

acute renal insufficiency

Question 17

Histopathologic findings in renal disease associated with infective endocarditis

Answer 17

Focal and segmental endopapillary proliferative glomerulonephritis with focal crescents

Question 18

Malarial strain producing a set of symptoms ranging in severity from transient proteinuria to microscopic hematuria to resistant nephrotic syndrome

Answer 18

P. malariae

Question 19

Most common histologic findings in syphyllis nephropathy

Answer 19

Membranous nephropathy