Glycoproteins

Question 1

What are glycoproteins?

Answer 1

Proteins with carbs attached

Question 2

1st Class of Glycoproteins: Glycoproteins

Answer 2

The protein is the largest component by weight
Protein (>50%) > Carb
Important role: membrane proteins

Question 3

2nd Class of Glycoproteins: Proteoglycans

Answer 3

The protein is attached to a particular type of polysaccharide called a glycosaminoglycan
Carb (~75%) > Protein
Important role: structural, lubricants

Question 4

3rd Class of Glycoproteins: Mucins/Mucoproteins

Answer 4

The protein is characteristically attached to the carb by N-acetylgalactosamine
Carb > Protein
Important role: lubricants

Question 5

Glycosaminoglycans are composed of

Answer 5

repeating units of a disaccharide, one of which is a derivative of an amino sugar and one of which carries a (-) charge, either as a carboxylate or sulfate

Question 6

Lectins

Answer 6

Glycan-binding proteins bind to specific oligosaccharides on the cell surface, regions of interaction (cells and their environments)
- Cell recognition

Question 7

Selectins

Answer 7

A particular class of glycan-binding protein
- Help immune system cells bind to site of injury