Drawing Gluconeogenesis Flashcards
What is the first step in gluconeogenesis and draw it?
(2) pyruvate -> (2) oxaloacetate
2ATP -> 2ADP
What is the enzyme that catalyzes pyruvate to oxaloacetate?
Pyruvate carboxylase
Draw oxaloacetate
(-)O-C(=O)-C(=O)-CH2-C(=O)-O(-)
What is the second step in gluconeogenesis and draw it
(2) oxaloacetate -> (2) phosphoenolpyruvate
2GTP -> 2GDP
What is the enzyme for oxaloacetate to phosphoenolpyruvate?
PEP carboxykinase
What is step 3 of gluconeogenesis and draw it
(2) Phosphoenolpyruvate < > (2) 2-phosphoglycerate
What is the enzyme for phosphoenolpyruvate to 2-phosphoglycerate?
Enolase
What is step 4 of gluconeogenesis and draw it
(2) 2-phosphoglycerate < > (2) 3-phosphoglycerate
What is the enzyme for 2-phosphoglycerate to 3-phosphoglycerate?
Phosphoglycero-mutase
What is step 5 of gluconeogenesis and draw it
(2) 3-phosphoglycerate < > (2) 1,3-bisphosphoglycerate
2ATP -> 2ADP
What is the enzyme for 3-phosphoglycerate to 1,3-bisphosphoglycerate?
Phosphoglycerate kinase
What is step 6 of gluconeogenesis and draw it
(2) 1,3-bisphosphoglycerate < > (2) glyceraldehyde 3-phosphate
2NADH + H+ -> 2NAD+ + 2Pi
What enzyme catalyzes 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphate?
Glyceraldehyde 3-phosphate dehydrogenase
What is step 7 of gluconeogenesis and draw it
(2) Glyceraldehyde 3-phosphate < > (2) Dihydroxyacetone phosphate
What enzyme catalyzes glyceraldehyde 3-phosphate to dihydroxyacetone phosphate?
Triose phosphate isomerase