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Glycolysis/Krebs Flashcards

1
Q

GLYCOLYSIS

What is glucose converted into?

A

Glucose-6-phosphate

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2
Q

GLYCOLYSIS

What is glucose-6-phosphate converted into?

A

Fructose-6-phosphate

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3
Q

GLYCOLYSIS

What is fructose-6-phosphate converted into?

A

Fructose-1,6-biphosphate

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4
Q

GLYCOLYSIS

What is fructose-1,6-biphosphate converted into?

A

Dihydroxyacetonephosphate -> 3-phosphoglyceraldehyde (x2)

3-phosphoglyceraldehyde (x2)

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5
Q

GLYCOLYSIS

What is 3-phosphoglyceraldehyde converted into?

A

1,3-biphosphoglyerate

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6
Q

GLYCOLYSIS

What is 1,3-biphosphoglycerate converted into?

A

3-phosphoglycerate

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7
Q

GLYCOLYSIS

What is 3-phosphoglycerate converted into?

A

2-phosphoglycerate

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8
Q

GLYCOLYSIS

What is 2-phosphoglycerate converted into?

A

Phosphoenolpyruvate

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9
Q

GLYCOLYSIS

What is phosphoenolpyruvate converted into?

A

Pyruvate

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10
Q

What is pyruvate used in?

A

Converted into lactate

Substrate for Kreb’s cycle

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11
Q

GLYCOLYSIS

What enzyme catalyses the conversion of glucose to glucose-6-phosphate?

A

Hexokinase

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12
Q

GLYCOLYSIS

What enzyme catalyses the conversion of glucose-6-phosphate to fructose-6-phosphate?

A

Phosphohexose isomerase

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13
Q

GLYCOLYSIS

What enzyme catalyses the conversion of fructose-6-phosphate to fructose-1,6-biphosphate?

A

Phosphofructokinase-1

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14
Q

GLYCOLYSIS

What enzyme catalyses the conversion of fructose-1,6-biphosphate to 3-phosphoglyceraldehyde?

A

Fructose biphosphate aldolase

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15
Q

GLYCOLYSIS

What enzyme catalyses the conversion of dihydroxyacetone phosphate to 3-phosphoglyceraldehyde?

A

Triose phosphate isomerase

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16
Q

GLYCOLYSIS

What enzyme catalyses the conversion of 3-phosphoglyceraldehyde to 1,3-biphosphoglycerate?

A

Glyceraldehyde-3-phophate dehydrogenase

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17
Q

GLYCOLYSIS

What enzyme catalyses the conversion of 1,3-biphosphoglycerate to 3-phosphoglycerate?

A

Phosphoglycerate kinase

18
Q

GLYCOLYSIS

What enzyme catalyses the conversion of 3-phosphoglycerate to 2-phosphoglycerate?

A

Phosphoglycerate mutase

19
Q

GLYCOLYSIS

What enzyme catalyses the conversion of 2-phosphoglycerate to phosphoenolpyruvate?

20
Q

GLYCOLYSIS

What enzyme catalyses the conversion of phosphoenolpyruvate to pyruvate?

A

Pyruvate kinase

21
Q

KREBS CYCLE

What is citrate converted into?

A

Isocitrate

22
Q

KREBS CYCLE

What is isocitrate converted into?

A

alpha ketoglutarate

23
Q

KREBS CYCLE

What is alpha ketoglutarate converted into?

A

Succinyl coenzyme A

24
Q

KREBS CYCLE

What is succinyl coenzyme A converted into?

25
KREBS CYCLE | What is succinate converted into?
Fumarate
26
KREBS CYCLE | What is fumarate converted into?
Malate
27
KREBS CYCLE | What is malate converted into?
Oxaloacetate
28
KREBS CYCLE | What is oxaloacetate converted into?
Citrate
29
KREBS CYCLE | What enzyme catalyses the conversion of citrate to isocitrate?
Aconitase
30
KREBS CYCLE | What enzyme catalyses the conversion of isocitrate to alpha ketoglutarate?
Isocitrate dehydrogenase
31
KREBS CYCLE | What enzyme catalyses the conversion of alpha ketoglutarate to succinyl coenzyme A?
alpha ketoglutarate dehydrogenase
32
KREBS CYCLE | What enzyme catalyses the conversion of succinyl coenzyme A to succinate?
Succinyl coenzyme A synthetase
33
KREBS CYCLE | What enzyme catalyses the conversion of succinate to fumarate?
Succinate dehydrogenase
34
KREBS CYCLE | What enzyme catalyses the conversion of fumarate to malate?
Fumarate hydratase
35
KREBS CYCLE | What enzyme catalyses the conversion of malate to oxaloacetate?
Malate dehydrogenase
36
KREBS CYCLE | What enzyme catalyses the conversion of oxaloacetate to citrate?
Citrate synthase
37
What is the relationship between glycolysis and the krebs cycle?
Pyruvate -> Acetyl CoA + CO2 | Acetyl CoA activates the conversion of oxaloacetate to citrate
38
Which reactions in glycolysis involve ATP hydrolysis?
Glucose -> Glucose-6-phosphate | Fructose-6-phosphate -> Fructose-1,6-bisphosphate
39
What steps of glycolysis produce ATP?
1,3 bisphosphoglycerate -> 3 phosphoglycerate | phosphoenolpyruvate - > pyruvate
40
What is the net gain from glycolysis per molecule of glucose?
2 NADH | 2 ATP
41
What is the rate limiting enzyme of the Krebs cycle?
Isocitrate dehydrogenase
42
What is the net output of Krebs
2 ATP | 6 NADH

Questions i got wrong (6 decks)

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