glycolysis Flashcards
glycolysis investment
glucose to fructose-1, 6-bisphosphate
splitting stage
Fructose-1, 6-bisphosphate to glyceraldehyde-3-phosphate
energy conservation
glyceraldehyde-3-phosphate to pyruvate
glucose to glucose-6-phosphate
phosphate group added, negative charge means it wont pass through membrane
catalysed by hexokinase
kinase
any enzyme that phosphorylates using ATP
reasons glycolysis needs control
link supply with demand
allows cells / organisms to respond to environment
maintain constant internal environment
pyruvate entry into CAC
oxidative decarboxylation
thiamine pyrophosphate - thiamine
pyruvate dehydrogenase
FAD-FADH2
thiamine
found in grain husks and wheat
beri beri
bitamin B1 deficiency
extreme weakness
numbness of limbs
loss of appetite
pyruvate to lactate
anaerobic conditions
lactate dehydrogenase
oxidative phosphorylation
takes place inside mitochondria
formation of ATP by transferring electrons to NADH
Q cycle
mechanism that couples electron transfer from QH2 to cytochrome C
carbon monoxide
high affinity to Hb reduces amount of oxygen getting to cells
cyanide
binds to complex IV (cytochrome C oxidase) and blocks oxidative phosphorylation
salicylate
forms pores in inner membrane
protons pass through w/o generating ATP