glycolysis Flashcards

1
Q

glycolysis investment

A

glucose to fructose-1, 6-bisphosphate

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2
Q

splitting stage

A

Fructose-1, 6-bisphosphate to glyceraldehyde-3-phosphate

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3
Q

energy conservation

A

glyceraldehyde-3-phosphate to pyruvate

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4
Q

glucose to glucose-6-phosphate

A

phosphate group added, negative charge means it wont pass through membrane
catalysed by hexokinase

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5
Q

kinase

A

any enzyme that phosphorylates using ATP

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6
Q

reasons glycolysis needs control

A

link supply with demand
allows cells / organisms to respond to environment
maintain constant internal environment

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7
Q

pyruvate entry into CAC

A

oxidative decarboxylation
thiamine pyrophosphate - thiamine
pyruvate dehydrogenase
FAD-FADH2

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8
Q

thiamine

A

found in grain husks and wheat

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9
Q

beri beri

A

bitamin B1 deficiency
extreme weakness
numbness of limbs
loss of appetite

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10
Q

pyruvate to lactate

A

anaerobic conditions

lactate dehydrogenase

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11
Q

oxidative phosphorylation

A

takes place inside mitochondria

formation of ATP by transferring electrons to NADH

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12
Q

Q cycle

A

mechanism that couples electron transfer from QH2 to cytochrome C

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13
Q

carbon monoxide

A

high affinity to Hb reduces amount of oxygen getting to cells

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14
Q

cyanide

A

binds to complex IV (cytochrome C oxidase) and blocks oxidative phosphorylation

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15
Q

salicylate

A

forms pores in inner membrane

protons pass through w/o generating ATP

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16
Q

electron motive force

A

electrons flow from NADH or FADH2 to O2
flow via a series of proton complexes located in inner mitochondrial membrane
results in pumping of protons H+ out of mitochondrial matrix into intermembrane space

17
Q

proton motive force

A

uneven distribution of protons generates pH gradient and transmembrane electrical potential