Glycogen and Lipid Flashcards
what bonds are in glycogen
aplha 1-6 form branching chain
alpha 1-4 formbetween glycosidic bonds
what structure does glycogen stroage take and why is it important to store it that way
- glycogen dimers = glycogenin
- dont affect osmosis and beasue of lots of branches branching enzyme can hydrolayse quickly releasing energy faster
formula for glycogenesis
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formula for glycogenolysis
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how much glycogen stored in the m and liver what happens differently in the muscle and liver why cant they switch jobs
muscle (300g) used that glycogen for energy liver used to to act as glucose buffer in the blod (100g)
- mscle doent have g-6-phosphatase so cant convert G^ to glucose
regualtion of glycogen metabolism
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what are 32 inheritied diseased of glycogen storage
- mcardles disease where glycogenphosphorylase not in muscle so break down glycogen stores
- von Gierkes disease = g 6 phosphatase deficiency in the liver so cant make glucose
gluconeogenesis
where doweget lactate?
- cori cycle
is there any synthsis of glucose from acteyl co a?
no because pyrivate dehydroenase (5 enyzymescomplex) is irreversible
regulationof gluconeogenesis
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tiem course for glucose utilisaton
0-2 hr blood g
up to 8-10 hrs glycogen stores
10+ gluconeogenesis
lipid formula to TAG ]how is lipidstoredand where
glycerol + 3 FA ==(esterifcation) TAG +3 h20
+ 3h20 TAG =(lipolysis) 3FA +glycerol
-anhydrous state in adipose tissue
TAG metabolism pthway
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where does lipgenesis occur?
what metabolite does it use?
main 2 enxymes involved?
what does reaction require
liver
pyruvate
acteyl co a carboxylase
fatty acid synthesis complex
atp and nadph
lipogenesis
differnces between FA oxidation adn synthesis
