Cholesterol Flashcards

1
Q

how are lipids transported

A

2% (mostly FA) carried bound noncovalently to albumin but theres a limited capacity of 3mmol/L

98% of lipids are carried bound noncovalently to lipoprotein particles consiting of cholesterol, cholesterol esters, proteins, TAG

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2
Q

total serum cholesterol?

A

<5mmol/L

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3
Q

what are plasma lipoproteins

A
  • complex that contain different lipids (cholesterol, cholesterol esters, TAG, phospholipids)
  • membranes are phospholipid monolayer with small amounts of cholesterol
  • associated with specific apolipoproteins ; which are intergral or peripheral.
    • peripheral: apoC (binds to LPL on adipocytes and muscle) apoE (binds to LDL receptor on hepatocytes)
    • intergral: apoA and apoB (apoB-48 added before entering lymphatic/apoB-100 added during fromationof apoC and apoE)
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4
Q
A
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