Glucose Intolerance and Cholesterol Flashcards

1
Q

what is diabetes mellitus

A

abnormal production or use of insulin from the pancreas

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2
Q

what are the two types of problems associated with diabetes mellitus

A

production problem - not enough beta cell production, or abnormal release

use problems - peripheral tissue receptor dysfunction (resistance), or abnormal hormones that influence insulin or blood glucose

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3
Q

what are the two types of diabetes mellitus

A
type 1
onset early 
requires insulin (deficient)
production deficit  
type 2 
onset later 
less severe 
overweight 
tissue resistance
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4
Q

normal glucose tolerance is dependent on what

A

liver conversion to glycogen

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5
Q

high levels of glucose suppress what (glycogen)

what does epinephrine do

A

glycogen conversion to glucose

epinephrine causes glycogen conversion to glucose

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6
Q

glucagon is released during what

A

hypoglycemia

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7
Q

what increases glycogen levels

HOW

A

cortisol, cortisone

converts amino acids into glycogen which converts to glucose

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8
Q

gluconeogenesis is produced from what

A

fats and proteins

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9
Q

what are the symptoms of glucose intolerance

A

polydipsia, polyuria, ketonuria, acetone breath, neurological adrengergic, weight loss (classic)

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10
Q

what is whipples triad

A

responses to hypoglycemia

symptoms, low values, response to therapy

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11
Q

what should your cholesterol levels be

low risk, moderate, high

A

< 200

low risk - <200
moderate - 200-240
high risk - > 240

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12
Q

what should your LDL levels be

A

< 130

optimal - <100
above optimal - 100-129
borderline high - 130-159
high - 160-189

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13
Q

what should your HDL levels be

A

Males > 45

Females > 55

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14
Q

what should your TAG levels be

A

Males < 160

Females < 135

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15
Q

what is a small amount of ingested fats, but overtime they lead to serious consequences

what is the source

A

cholesterol

animal fat

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16
Q

risk of what increases or decreases significantly within the normal cholesterol value

as risk increases, what is needed to know

A

heart or vascular disease

need to know what type of cholesterol is present

17
Q

what are the risk factors for increased LDLs

A

smoking
age - M>45 and F>55
BP > 140/90
family history of HD

18
Q

what is LDL equation

A

LDL = total cholesterol - (HDL + (TRIG/5))

19
Q

less than 40 for males and less than 50 for females HDL indicates what

A

increase risk of HD

20
Q

above 60 for HDL is considered what

A

protective

21
Q

cholesterol/HDL ratio should be

A

5 for males

4.4 for females

22
Q

triglycerides come from what source

A

ingested fats

better known as chylomicrons

23
Q

excess carbs CHO convert into __ by the liver

A

VLDLs

24
Q

TG/HDL ratio should be

A

less than 3.5