*Glomerulonephritis

Question 1

What comprises the renal parenchyma?

Answer 1

Tubules

Interstitium

Glomeruli

Question 2

What is the most common cause of end stage renal failure?

Answer 2

Diabetes

(2nd is glomerulonephritis)

Question 3

What is glomerulonephritis?

Answer 3

Immune-mediated disease of the kidney affecting glomeruli

Question 4

What can initiate the immune response within the glomeruli within glomerulonephritis?

Answer 4

Planted antigen

Self antigen (true autoimmunity)

Antibody-antigen complexes becoming trapped

Question 5

What are the different types of lesions in glomerulonephritis?

Answer 5

Proliferative

Non-proliferative

Question 6

What is a proliferative lesion in glomerulonephritis?

Answer 6

Damage to mesangial or endothelial cells

Question 7

What is the difference between endothelial and mesangial damage in terms of presentation?

Answer 7

Creatinine is normal in mesangial damage and rasied in endothelial

Question 8

In which type of lesion in GN involves red cell casts in the urine?

Answer 8

Proliferative

Question 9

What is a non-proliferative lesion in GN?

Answer 9

Damage to podocytes

Question 10

Which type of lesion causing GN involves proteinuria?

Answer 10

Non-proliferative