Glomerular nephritic syndromes of the kidney

Question 1

Anti-Glomerular Basement membrane glomerular nephritis

Glomerular nephritis and pulmonary hemorrhage

Peaks in 20s-30s males, and agin equally in 60s-70s

Anti-GBM Antibodies

Plasma Exchange

Answer 1

Goodpasture

Question 2

IgA deposition in glomerular mesangium

Hematuria w/ URI; proteinura;

More common in males and children

Monitory only if no risk for progression.

Answer 2

IgA Nephropathy/Berger Disease

Question 3

Most common in children

Arthralgia, purpuric skin lesions on lower extremities (predominatly)

Small vessel vasculiitis associated with IgA depsotion in vessel walls

Tx: Steroids

Answer 3

Henoch-Schönlein Purpura

Question 4

Encompasses wegner granulomatosis, microscopic polyangitis and Chur-Strauss

Postive ANCA

Fever, malaise, wt. loss, upper & lower resp tract infections, purpura

Tx: Steroids

Answer 4

Post-immune glomerulonephritis