Glomerular Filtration Flashcards
1
Q
of blood entering glomerulus, how much is filtered?
A
20% filtered, and of this, 19% is reabsorbed into bloodstream
2
Q
what crosses GBM, crosses GBM but reabsorbed in proximal tubule, does not cross GBM
A
Crosses GBM
- Water
- Electrolytes
- Urea
- Creatinine
Crosses GBM but reabsorbed in proximal tubule
- Glucose
- Low molecular weight proteins (α2 microglobulin)
Does not cross GBM
- Cells (RBC, WBC)
- High molecular weight proteins (albumin, globulins)
3
Q
what arteriole has high hydostatic pressure?
A
afferent arteriole
4
Q
golden rule of circulation?
A
if have high resistance, pressure will be increased downstream and reduced upstream
5
Q
outline the methods of intrinsic and extrinsic control of the kidneys
A
intrinsic:
- afferent arteriolar vasodilation
- efferent arteriolar vasoconstriction
extrinsic:
- sympathetic VC nerves- afferent & efferent constriction
- circulating catecholamines- mainly afferent
- Angiotensin II- mainly efferent
