GLOMERULAR DISEASE Flashcards

1
Q

Types of Renal Disease

A

GTIV
Glomerular - Immune Mediated
Tubular - infectious and toxic
Interstitial - infectious and toxic
Vascular - cellular perfusion Morphology and Functional changes un kidney

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2
Q

Type of Glomerular Disease

A

Nephrotic Syndrome

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3
Q

Increased Permeability of glomeruli

A

Nephrotic Syndrome

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4
Q

Nephrotic Syndrome is characterized with

A

Heavy proteinuria
Hypoproteinemia
Hyperlipedemia

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5
Q

Types of Glomeruloneohritis

A

Acute glomerulonephritis
Focal Segmental
Membranoproliferative
IgA
Chronic

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6
Q

Other term for Acute gromulonephritis

A

Poststreptococcal glomerulonephritis

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7
Q

Causative agent of Acute glomerulo

A

Group A beta streptococci

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8
Q

Protein involved in the cell wall of Group A beta strep

A

M protein

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9
Q

Sclerosis of glomeruli

A

Focal Segmental

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10
Q

Characteristics of Focal Segmental

A

Focal (some parts of glomeruli)
Segmental (specific part of glomerulus)
Proteinuria

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11
Q

Elevated ASO titer i associated with

A

Acute glomerulonephritis

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12
Q

Cellular proliferation in Mesangium

A

Membranoproliferative

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13
Q

Other characteritics of Membranoproliferative Glomerulo

A

Leukocyte infiltration
Thickening of glomeruli basement membrane

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14
Q

Deposition of IgA in Mesangium

A

IgA nephropathy

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15
Q

Slow and silent type of glomerulonephritis

A

Chronic

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16
Q

80% of chronic is due to

A

Previous infection with glomerulonephritis

17
Q

20% of chronic

A

Unrecognized form of glomerulonephritis

18
Q

2 types of Acute tubular necrosis

A

Ischemic ATN
Toxic ATN

19
Q

Characterized with hypotensive, decrease renal perfusion, ischemia

A

Ischemic ATN

20
Q

Ischemic ATN is associated with

A

Sepsis
Shock
Trauma

21
Q

2 types of toxic ATN

A

Endogenous (normal-excessive)
Exogenous (absorbed-ingested)

22
Q

Endogenous toxic ATN causes

A

HUMI
Hemoglobin
Uric acid
Myoglobin
Immunoglobulin light chain

23
Q

Exogenous toxic ATN

A

TAR-RIC
therapeutic drug
Anesthetic
Radiographic media material
Recreational drugs
Industrial materials
Chemotherapeutic drug

24
Q

PROXIMAL TUBULAR DYSFUNCTION (impaired reabsorption)

A
  • Renal Glucosuria
  • Cystinuria (Cysteine and Dibasic AA)
  • Hartnups Disease (Monoamino-Monocarboxylic)
    Barrter’s syndrome
    Idiopathic hypercalciura
    Renal tubular Acidosis type 2
25
Q

PTD: Glucosuria

A

Impaired reabsorption of GLUCOSE

26
Q

Cystinuria and Hartnups

A

Impaired reabsorption of AMINO ACID

27
Q

PTD: Barrter’s syndrome

A

Impaired reabsorption of SODIUM

28
Q

PTD: Renal Tubular Acidosis type II

A

Impaired reabsorption of BICARBONATE

29
Q

Impaired reabsorption of CALCIUM

A

Idiopathic hypercalciuria

30
Q

PTD: Excessive Reabsorption condition

A

Gordons’s syndrome
Hypocalciuric Familial Hypercalcemia
PseudoHYPO parathyroidism

31
Q

Gordons syndrome

A

PTD: excessive reabsorption of SODIUM

32
Q

Hypocalciuric familial hypercalcemia

A

PTD: excessive reabsorption of CALCIUM

33
Q

PseudoHYPO parathyroidism

A

PTD: excessive reabsorption of PHOSPHATE

34
Q

LOSS OF PROXIMAL TUBULAR FUNCTION

A

Fanconi Syndrome