GLOMERULAR DISEASE Flashcards
Types of Renal Disease
GTIV
Glomerular - Immune Mediated
Tubular - infectious and toxic
Interstitial - infectious and toxic
Vascular - cellular perfusion Morphology and Functional changes un kidney
Type of Glomerular Disease
Nephrotic Syndrome
Increased Permeability of glomeruli
Nephrotic Syndrome
Nephrotic Syndrome is characterized with
Heavy proteinuria
Hypoproteinemia
Hyperlipedemia
Types of Glomeruloneohritis
Acute glomerulonephritis
Focal Segmental
Membranoproliferative
IgA
Chronic
Other term for Acute gromulonephritis
Poststreptococcal glomerulonephritis
Causative agent of Acute glomerulo
Group A beta streptococci
Protein involved in the cell wall of Group A beta strep
M protein
Sclerosis of glomeruli
Focal Segmental
Characteristics of Focal Segmental
Focal (some parts of glomeruli)
Segmental (specific part of glomerulus)
Proteinuria
Elevated ASO titer i associated with
Acute glomerulonephritis
Cellular proliferation in Mesangium
Membranoproliferative
Other characteritics of Membranoproliferative Glomerulo
Leukocyte infiltration
Thickening of glomeruli basement membrane
Deposition of IgA in Mesangium
IgA nephropathy
Slow and silent type of glomerulonephritis
Chronic
80% of chronic is due to
Previous infection with glomerulonephritis
20% of chronic
Unrecognized form of glomerulonephritis
2 types of Acute tubular necrosis
Ischemic ATN
Toxic ATN
Characterized with hypotensive, decrease renal perfusion, ischemia
Ischemic ATN
Ischemic ATN is associated with
Sepsis
Shock
Trauma
2 types of toxic ATN
Endogenous (normal-excessive)
Exogenous (absorbed-ingested)
Endogenous toxic ATN causes
HUMI
Hemoglobin
Uric acid
Myoglobin
Immunoglobulin light chain
Exogenous toxic ATN
TAR-RIC
therapeutic drug
Anesthetic
Radiographic media material
Recreational drugs
Industrial materials
Chemotherapeutic drug
PROXIMAL TUBULAR DYSFUNCTION (impaired reabsorption)
- Renal Glucosuria
- Cystinuria (Cysteine and Dibasic AA)
- Hartnups Disease (Monoamino-Monocarboxylic)
Barrter’s syndrome
Idiopathic hypercalciura
Renal tubular Acidosis type 2
PTD: Glucosuria
Impaired reabsorption of GLUCOSE
Cystinuria and Hartnups
Impaired reabsorption of AMINO ACID
PTD: Barrter’s syndrome
Impaired reabsorption of SODIUM
PTD: Renal Tubular Acidosis type II
Impaired reabsorption of BICARBONATE
Impaired reabsorption of CALCIUM
Idiopathic hypercalciuria
PTD: Excessive Reabsorption condition
Gordons’s syndrome
Hypocalciuric Familial Hypercalcemia
PseudoHYPO parathyroidism
Gordons syndrome
PTD: excessive reabsorption of SODIUM
Hypocalciuric familial hypercalcemia
PTD: excessive reabsorption of CALCIUM
PseudoHYPO parathyroidism
PTD: excessive reabsorption of PHOSPHATE
LOSS OF PROXIMAL TUBULAR FUNCTION
Fanconi Syndrome
