CEREBROSPINAL FLUID Flashcards

1
Q

3RD MAJOR BODY FLUID

A

CEREBROSPINAL FLUID

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2
Q

Function of CSF

A
  • supply nutrients to the nervous system
  • remove metabolic waste
  • produce a mechanical barrier to cushion brain and spinal
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3
Q

Outermost layer; directly lines skull and vertebral canal

A

DURA MATER (TOUGH MOTHER)

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4
Q

Lines/Covers the brain

A

MENINGES

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5
Q

Spider-like appearance (filamentous)

A

Arachnoid mater

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6
Q

Located between PM and AM where CSF flows

A

SUBARACHNOID SPACE

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7
Q

Innermost layer, directly lines brain and spinal cord

A

Pia Mater (tough mother)

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8
Q

Filters plasma to produce CSF

A

Choroid plexus

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9
Q

Rate of production/filtration

A

20 mL/hr

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10
Q

Choroid plexus are composed of

A

Tight junctions of endothelial cells which make up BB

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11
Q

Prevents passage of many molecules, protects brain from infection

A

Blood brain barrier

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12
Q

Regulates CSF production by reabsorbing circulating CSF

A

Arachnoid villi/Granulations

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13
Q

LUMBAR PUNCTURE (spinal tap) is inserted

A

3rd and 4th
4th and 5th

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14
Q

Cisternal Puncture

A

Inserted directly below OCCIPITAL BONE

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15
Q

Volume collected

A

20 mL

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16
Q

TUBES FOR COLLECTION

A

1st - Chemistry/Serology (frozen)
2nd - Microbiology (Room Temp)
3rd - Hematology (Refrigerated)

17
Q

1 TUBE ONLY

A

MICRO —> HEMA —> CHEM/SERO

18
Q

CSF VOLUME

A

ADULT: 90-150 mL
NEONATES: 10-60 mL

19
Q

Crystal Clear

A

Normal

20
Q

Hazy/turbid/Milky/Cloudy

A
  • Meningitis
  • > 20 uL
  • > 400 /uL RBC
  • Microorganisms
  • Proteins and Lipids
21
Q

Slight amount of Oxyhemoglobin

A

Pink

22
Q

Heavy hemolysis

A

Orange

23
Q

Yellow

A

Oxyhemoglobin —> Bilirubin

24
Q

Increased Protein >150 mg/dL

A

Yellow
Due to damage BBB

25
Q

Presence of Melanin

A

Brownish
Meningeal Melanosarcoma

26
Q

Presence of Carotene

A

Carotene - Precursor of vitamin A
Hypervitaminosis A
- Orange

27
Q

Red-Orange Color

A

Rifampicin

28
Q

Iodine

A

Yellowish (Antiseptic contamination)

29
Q

Bloody

A

Increased RBC >600 uL

30
Q

Oily

A

Radiographic Contrast Media

31
Q

Clotted (Fibrinogen)

A

Menigitis
Froin syndrome
Traumatic Tap

32
Q

Pellicle (web-like)

A

Tubular Meningitis
Refrigerated

33
Q

Water-like

A

Normal

34
Q

Viscous

A

Metastatic mucin-producing adenocarcinoma
Cryptoccocus menigitis (Polysaccharide capsule)
Liquid Nucleus Pulposus