Glands Of Digestion Flashcards

1
Q

Gallbladder release bile in response to

A

CCK and the vagus nerve

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2
Q

What is the surface epithelium of the gallbladder

A

Simple columnar

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3
Q

Which major luminal wall layer is significantly absent in gallbladder

A

Submucosa

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4
Q

Does the Muscularis externa of the gallbladder have normal pattern

A

NO

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5
Q

What are the two cell types in the mucosa

A

Clear cells-cholangiocytes

Brush cells

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6
Q

What is the function of clear cells

A

Concentrate bile by absorbing water, have many microvilli

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7
Q

What is the function of brush cells

A

Produce mucinogen- for lubrication

FEW IN NUMBER

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8
Q

Where is the lamina propia mc found in the gallbladder

A

Neck, often possess small mucous glands

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9
Q

What is the function of lamina propia in the gallbladder

A

Lubricate the narrow neck lumen

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10
Q

Is the Muscularis mucosa present in the gallbladder

A

NO

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11
Q

Does the gallbladder have a Submucosa?

A

ABSENT VERY UNSUAL

This is why gallstones develop

TQ!!!!!

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12
Q

What kind of pattern does the Muscularis externa have in the gallbladder

A

Not a normal pattern, consists of thin smooth muscle layer with DISORGANIZED muscle arrangement

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13
Q

Is the gallbladder attach to the liver via adventitia or serousa?

A

Mostly serosa

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14
Q

What kind of bile works best with small intestines

A

Cystic

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15
Q

What major secretory portion of the pancreas is the largest

A

Exocrine- enzyme producing

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16
Q

Which pancreatic cells help buffer chyme?

A

Centroacinar and cuboid cells in the pancreatic intercalated ducts

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17
Q

The endocrine pancreas is

A

Islets of langerhans producing hormones

18
Q

Exocrine pancreas does

A

Serous acini producing digestive enzymes

19
Q

LArgest portion of the pancreas is which portion

20
Q

Serous acini of the pancreas secretion is controlled by?

A

CCK, and acetylcholine from parasympathetic nerves

21
Q

Pancreatic ducts secrete H2O and HCO3 and is controlled by

A

SECRETIN and acetylcholine from parasympathetic nerves

Bicarbonate to neutralize chyme in duodenum

22
Q

What are centroacinar cells

A

In pancreas located next to acinar cells

23
Q

What are centroacinar cells

A

Cells along with the cuboid cells in intercalated pancreatic ducts

24
Q

What does centroacinar cells produce

A

Alkaline fluid with large quantities of bicarbonate ions released into duodenum

25
What wraps around of the pancreatic ducts
Collagen rich CT tissue Function- provide extra protection from the possible leaking digestive enzymes
26
What is the largest gland in the body with endocrine and exocrine functions
LIVER
27
Why are the hexagonal shaped lobules in liver hard to distinguish
Cue to lack of CT tissue between lobules
28
What are hepatocytes
Microvilliated cuboidal cells processing lateral bile canaliculi between adjacent hepatocytes
29
HOw does bile move from the hepatocytes toward the bile duct bronchi in the
Portal triad
30
What do bile canaliculi do
Collect bile
31
What is the function of kupffer cells (stellate macrophages) in the liver
Resident macrophages, develop from monocytes Phagocytosis of debris and red blood cells, act as APC
32
What are Ito cells (hepatic stellate cells) and functions
Store lipids fro immediate use, store vitamin A, produce collagen I,III,IV and growth factors
33
Ito cells (hepatic stellate cells) dont produce
College type II
34
What are Pit cells in the liver
Natural killer cells
35
What are hepatic progenitor cells
Likely present and responsible for REGENERATIVE CAPABILITIES
36
What does the portal triads include
1. hepatic artery-smallest 2. Portal vein-largest 3. bile duct-dark stain They also have cholangiocytes
37
What are the dilated, fenestrated thin walled vessels found between rows of hepatocytes
Hepatic sinusoids 75% venous 25% arterial blood
38
What is the central vein in the liver
Fenestrated thin walled vessel that collects blood from the hepatic sinusoids
39
Blood flows from the __________ towards the __________
Portal triad, central vein
40
What is the space of Disse
Is the perisinusoidal space Space between the hepatocytes and the fenestrated hepatic sinusoids
41
Where does blood directly contact the microvilliated surfaces of hepatocytes
Space of Disse Flows slow enough so the cells can interact with blood, which is why the liver can take over the function of the spleen for 24-48 hours
42
What is Glissons capsule
Is dense irregular CT covered with serosa of the liver