Glands Of Digestion Flashcards

1
Q

Gallbladder release bile in response to

A

CCK and the vagus nerve

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2
Q

What is the surface epithelium of the gallbladder

A

Simple columnar

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3
Q

Which major luminal wall layer is significantly absent in gallbladder

A

Submucosa

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4
Q

Does the Muscularis externa of the gallbladder have normal pattern

A

NO

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5
Q

What are the two cell types in the mucosa

A

Clear cells-cholangiocytes

Brush cells

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6
Q

What is the function of clear cells

A

Concentrate bile by absorbing water, have many microvilli

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7
Q

What is the function of brush cells

A

Produce mucinogen- for lubrication

FEW IN NUMBER

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8
Q

Where is the lamina propia mc found in the gallbladder

A

Neck, often possess small mucous glands

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9
Q

What is the function of lamina propia in the gallbladder

A

Lubricate the narrow neck lumen

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10
Q

Is the Muscularis mucosa present in the gallbladder

A

NO

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11
Q

Does the gallbladder have a Submucosa?

A

ABSENT VERY UNSUAL

This is why gallstones develop

TQ!!!!!

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12
Q

What kind of pattern does the Muscularis externa have in the gallbladder

A

Not a normal pattern, consists of thin smooth muscle layer with DISORGANIZED muscle arrangement

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13
Q

Is the gallbladder attach to the liver via adventitia or serousa?

A

Mostly serosa

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14
Q

What kind of bile works best with small intestines

A

Cystic

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15
Q

What major secretory portion of the pancreas is the largest

A

Exocrine- enzyme producing

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16
Q

Which pancreatic cells help buffer chyme?

A

Centroacinar and cuboid cells in the pancreatic intercalated ducts

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17
Q

The endocrine pancreas is

A

Islets of langerhans producing hormones

18
Q

Exocrine pancreas does

A

Serous acini producing digestive enzymes

19
Q

LArgest portion of the pancreas is which portion

A

Exocrine

20
Q

Serous acini of the pancreas secretion is controlled by?

A

CCK, and acetylcholine from parasympathetic nerves

21
Q

Pancreatic ducts secrete H2O and HCO3 and is controlled by

A

SECRETIN and acetylcholine from parasympathetic nerves

Bicarbonate to neutralize chyme in duodenum

22
Q

What are centroacinar cells

A

In pancreas located next to acinar cells

23
Q

What are centroacinar cells

A

Cells along with the cuboid cells in intercalated pancreatic ducts

24
Q

What does centroacinar cells produce

A

Alkaline fluid with large quantities of bicarbonate ions released into duodenum

25
Q

What wraps around of the pancreatic ducts

A

Collagen rich CT tissue

Function- provide extra protection from the possible leaking digestive enzymes

26
Q

What is the largest gland in the body with endocrine and exocrine functions

A

LIVER

27
Q

Why are the hexagonal shaped lobules in liver hard to distinguish

A

Cue to lack of CT tissue between lobules

28
Q

What are hepatocytes

A

Microvilliated cuboidal cells processing lateral bile canaliculi between adjacent hepatocytes

29
Q

HOw does bile move from the hepatocytes toward the bile duct bronchi in the

A

Portal triad

30
Q

What do bile canaliculi do

A

Collect bile

31
Q

What is the function of kupffer cells (stellate macrophages) in the liver

A

Resident macrophages, develop from monocytes

Phagocytosis of debris and red blood cells, act as APC

32
Q

What are Ito cells (hepatic stellate cells) and functions

A

Store lipids fro immediate use, store vitamin A, produce collagen I,III,IV and growth factors

33
Q

Ito cells (hepatic stellate cells) dont produce

A

College type II

34
Q

What are Pit cells in the liver

A

Natural killer cells

35
Q

What are hepatic progenitor cells

A

Likely present and responsible for REGENERATIVE CAPABILITIES

36
Q

What does the portal triads include

A
  1. hepatic artery-smallest
  2. Portal vein-largest
  3. bile duct-dark stain

They also have cholangiocytes

37
Q

What are the dilated, fenestrated thin walled vessels found between rows of hepatocytes

A

Hepatic sinusoids

75% venous

25% arterial blood

38
Q

What is the central vein in the liver

A

Fenestrated thin walled vessel that collects blood from the hepatic sinusoids

39
Q

Blood flows from the __________ towards the __________

A

Portal triad, central vein

40
Q

What is the space of Disse

A

Is the perisinusoidal space

Space between the hepatocytes and the fenestrated hepatic sinusoids

41
Q

Where does blood directly contact the microvilliated surfaces of hepatocytes

A

Space of Disse

Flows slow enough so the cells can interact with blood, which is why the liver can take over the function of the spleen for 24-48 hours

42
Q

What is Glissons capsule

A

Is dense irregular CT covered with serosa of the liver