GIT Viruses

Question 1

Enterprises

Answer 1

ssRNA belongs to

Coxsackieviruses A, B

ECHO viruses

Poliovirus

Enteroviruses 68-71

Question 2

Characteristics of Enteroviruses

Answer 2

Replicate inside the GIT

fecal oral route

Resistant to disinfectants

Question 3

Poliovirus (disease , route , pathogenesis)

Answer 3

Poliomyelitis

Fecal-oral route

1. Replicate in GIT mucosa
2. Enter the blood (viraemia)
3. infect the anterior horn cells (spinal cord, brain stem, motor cortex )

Question 4

C/F of Poliomyelitis

Answer 4

Mild disease( fever, malaise, headache, nausea and vomiting )

Aseptic meningitis( last 2_20 days)

Paralytic Poliomyelitis( result from lower motor neuron damage )

Question 5

Poliomyelitis diagnosis

Answer 5

RT_PCR

serology

Question 6

Treatment and prevention of Poliomyelitis

Answer 6

Supportive treatment

Inactivated Poliovirus vaccine(salk vaccine)

Oral attenuated Poliovirus vaccine(sabin vaccine)

Question 7

Coxsackie viruses They are divided into 2 groups on the basis of

Answer 7

The lesions observed in suckling mice.

Question 8

Group A (1-24 types) Causes (4)

Answer 8

1. Herpangina: a sever febrile pharyngitis
2. Foot , Hand and mouth disease: Vesicular rash involving hand, feet and soft palate.
3. A septic meningitis
4. Diarrhea in children

Question 9

Group B (6 types) Causes

Answer 9

1. Pleurodynia : fever and Severe pleuritic chest pain.
2. Myocarditis.
3. Pancreatitis and DM. With B3,4 type.
4. Aseptic meningitis

Question 10

echoviruses (5)

Answer 10

1. Aseptic meningitis.
2. Skin rash disease (Dukes disease) fourth disease.
3. Infantile diarrhea
4. Respiratory tract infections.
5. Myocarditis

Question 11

Enterovirus 70

Answer 11

cause epidemics of acute haemorrhagic conjunctivitis

Question 12

Enterovirus 71

Answer 12

cause aseptic meningitis, encephalitis, paralytic disease.