Gardia Flashcards
Giardia duodenalis cause
giardiasis
The 2 forms of Giardia ?
Cyst ➡ when the are dehydrated
Trophozoite
Trophozoite looks like
Face ➡ binucleated
Trophozoite have …. flagella
8 2 anterior 2 posterior 2 ventral 2 caudal
Flagella arise from
Kinetosome
Giardia Trophozoite live in (location )
Upper part of small intestine ( duodenum , jejumum and upper ileum )
Ventral surface bears
The adhesive disk to adhere to intestinal surface
Giardia Trophozoite feeds on
Mucus ➡ that forms in response to irritation
Vitamin and Amino acid
Cyst Giardia forms as result of
Dehydration as the pass through the large intestine
Cyst morphology
Ovoid in shape
Thin cyct wall
4 nuclei
Flagella shorten within the cyst
Symptoms of giardiasis
Abdominal discomfort Acute or chronic diarrhea Other GI Symptoms Flatulence Gray, greasy, malodorous diarrhea.
Pathogenesis
malabsorption
Physical blockage and damage to microvilli
maldigestion
Route of infection
Ingesting cyst through contaminated water
Diagnosis
Trophozoite in diarrheic feces
Cyst in formed feces
ELISA test to detect soluble antigen