GIS W3 Microbiology of the lower GI

Question 1

This toxin irreversibly blocks the release of acetylcholine from the motoric end plate which results in muscle weakness and paralysis

Answer 1

botulinum toxin (neurotoxin)

Question 2

This enterotoxin binds to receptors in endothelial cell junctions, then generates pores in host mucosa cells

Answer 2

Clostridium prefringens

Question 3

What is the treatment for EHEC

Answer 3

Supportive (don’t use antibiotics –> could lead to release of massive amounts of toxin)