Giardia lamblia Flashcards

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1
Q

Which family does G. Lamlia belong to?

A

Hexamitidae

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2
Q

Is G. Lamlia zoonitic?

A

Yes

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3
Q

What are some G. Lamblia hosts?

A

Beavers, Dogs, Cattle, Sheep

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4
Q

How is G. lamblia transmitted?

A

Fecal-oral - > Ingestion of cysts;

Ingestion of cysts from contaminated water

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5
Q

What is a trophozoite?

A

A growing stage in the life cycle of some sporozoan parasites, when they are absorbing nutrients from the host.

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6
Q

What is the site where G. lamblia trophozites are found?

A

Upper part of small intestines (Duodenum)

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7
Q

How does G. lamblia trophozites multiply?

A

binary fission

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8
Q

What is the epidemiology of G. lamblia?

A

Worldwide distribution with prevalence reaching 20% in some areas

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9
Q

What are the symptoms of G. lamblia?

A
  • NO FEVER
  • mild to severe diarrhea
  • flatulence
  • Sulphorous belching
  • anorexia
  • crampy abdominal pains and epigastric tenderness
  • Mild to severe malabsorption syndrome
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10
Q

How is severe giardiasis characterized?

A

Production of light colored fatty stool.

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11
Q

Does villus atrophy occur with severe giardiasis?

A

Yes

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12
Q

How is G. lamblia diagnosed?

A

Direct: Cysts in stool. (10-36 days prior to
infection)
Indirect: theraputic trials - experiment with drugs

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13
Q

What is the treatment used for Giardia lamblia?

A

Quinacrine hydrochloride (Atabrine)
Metronidazole (Flagyl)
Tinidazole (Tindamax) USA

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14
Q

How can G. lamblia be controled/prevented?

A
  • Boiling or iodiniation of water before consumption.
  • good hygiene
  • cooking vegetables
  • proper sanitation
  • safe, piped water supply
  • No night soil fertilization
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15
Q

What are some other names for G. lamblia?

A

G. Intestinalis; G. duodenale

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16
Q

What is the PPP for Giardia lamblia?

A

10 days

symptoms may last days to months

17
Q

Which groups are at risk for Giardia lamblia?

A
  • Immunosuppressed
  • homosexuals
  • sewage workers
  • crowded institutions like day care
18
Q

Consider Giardia Lamblia infection with all chronic diarrhea, unexplained weight loss, and malabsorption syndrome.

A

Consider Giardia Lamblia infection with all chronic diarrhea, unexplained weight loss, and malabsorption syndrome.

19
Q

What does the severity of illness caused by Giardia Lamblia depend upon?

A
  • Number of organisms
  • Virulence of strain (Dog - low path)
  • Host immunity
  • Mucosal damage
  • Secondary bacterial colonization