GI Phys 4: Pancreas

Question 1

pancreatic roles (2)

Answer 1

1) protective role: bicarb and mucus

2) digestive role: enzymes

Question 2

Acinar cells

Answer 2

• protein synthesizing cell

- secrete enzymes and fluid

Question 3

Duct cell

Answer 3

• secrete HCO3 (bicarb)

- help transport ions and fluids

Question 4

Goblet cells

Answer 4

• secrete mucin

Question 5

important inactive enzyme for protein digestion (protease)

Answer 5

trypsinogen

Question 6

important active enzyme for carb digestions

Answer 6

a amylase

Question 7

important active enzyme for lipid digestion

Answer 7

colipase

Question 8

important active enzyme to inhibit trypsin

Answer 8

trypsin inhbitor

Question 9

protection against and activation of digestive enzymes (3)

Answer 9

1) many digestive enzymes are inactive in the pancreas (to protect it)
2) vesicles contain a trypsin inhibitor
3) low ph of vesicle prevents enzyme activation

Question 10

function of secretin

Answer 10

GI protection. Secretin targets the pancreatic duct to release bicarb. Secretin also feeds back to the stomach.

Question 11

greatest pancreatic secretion occurs during which phase

Answer 11

intestinal. stimulated by nutrients, primaily lipids and fatty acids. CCK!

Question 12

2 primary regulators of pancreatic secretion

Answer 12

lipids and fatty acids