GI Patho Part 2 Flashcards
Gross: Pesudopolyps Ulceration Loss of Haustra Crypt distortion
Ulcerative Colitis
Gross: Cobblestoning Fat Wrapping Fissure Thickened Wall Decreased Size of lumen
Crohn’s Disease
Occurs in colon Continuous lesions Limited to mucosa and submucosa Retgrograde development from rectum to proximal colon Pancolitis
Ulcerative Colitis
Occurs in Colon and Ileum
skip lesions
Transmural
Crohn’s Disease
Microscopic:
Crypt Abscesses in LP
Ulcerative Colitis
Microscopic:
Non-caseating granuloma
Crohn’s Disease
Most common site of volvulus
Rectum
Location of napkin-ring lesions in adenocarcinoma
Distal colon
Apple core in barium studies means marked lumen narrowing in what disease?
Colon Adenocarcinoma
Stage A duke staging system
Doesn’t extend beyond muscularis propria (mucosa only)
Nodes uninvolved
90% 5-year survival
Tumor that is derived from endocrine cells that is most commonly found in the appendix. Characterized by scant, pink granuar cytoplasm with round to oval stippled nucleus.
Carcinoid Tumor
Common hormones secreted by carcinoid tumor
Histamine
Bradykinin
Chromogranin
Serotonin
Tumor marker of Carcinoid tumor
Carcinoid Embryonic Antigen
Gross morphology of Chronic Passive Congestion of the liver
nutmeg liver
Most common benign lesion of liver
cavernous hemangioma
Adenoma caused by estrogen stimulation
Liver cell adenoma
HCC three major cause
Viral (HBV, HCV)
Alcohol
Aflatoxin
Tumor marker for HCC
Serum-a fetoprotein
Most common primary tumor of liver charactertized by hepatomegaly
Metastatic (from lung, breast, colon)
Most common primary tumor of the liver
HCC
Most common primary tumor of the liver in childhood
Hepatoblastoma
