GI/Nutrition Flashcards
causes of RUQ pain
biliary colic
acute cholecystitis
acute cholangitis
sphincter of oddi dysfxn
acute hepatitis
perihepatitis (fitz hugh curtis)
liver abscess
budd-chiari
portal vein thrombosis
acute cholangitis triad
fever
jaundice
RUQ pain
intense, dull discomfort in RUQ or epigastrum - n/v, diaphoresis - lasts 30 min, plateaus w.in 1 hr - benign PE
biliary colic
> 4-6 hr RUQ or epigastric pain, fever - abdominal guarding and murphy’s sign
acute cholecystitis
RUQ pain w. fatigue, malaise, n/v, anorexia - +/- jaundice, dark urine, light colored stools
acute hepatitis
RUQ pain with pleuritic component - pain may radiate to right shoulder
fitz hugh curtiz syndrome
2 mc sx of liver abscess
fever
abdominal pain
fever, abd pain w. distension, lower extremity edema, jaundice, GI bleeding, +/- hepatic encephalopathy
budd chiari syndrome
3 symptoms of portal vein thrombosis
abd pain
dyspepsia
GI bleed
causes of epigastric abd pain
acute MI
acute/chronic pancreatitis
PUD
GERD
gastritis/gastropathy
functional dyspepsia
gastroparesis
acute onset persistent upper abd pain radiating to the back
acute pancreatitis
mc sx of PUD
epigastric pain
epigastric pain w. heartburn, regurgitation, dysphagia
GERD
epigastric pain, heartburn, nausea, vomiting, hematemesis
gastritis/gastropathy
what is functional dyspepsia
one or more of the following:
postprandial fullness
early satiety
epigastric pain or burning
n/v, vomiting, abd pain, early satiety, bloating
gastroparesis
causes of LUQ pain
splenomegaly
splenic infarct
splenic abscess
splenic rupture
pain/discomfort in LUQ, left shoulder pain, early satiety
splenomegaly
severe LUQ pain
splenic infarct
fever, LUQ tenderness
splenic abscess
LUQ pain, left chest wall or left shoulder pain - worse w. inspiration
splenic rupture
causes of lower abdominal pain
appendicitis
diverticulitis
nephrolithiasis
pyelonephritis
acute urinary retention
cystitis
infectious colitis
describe appendicitis pain
intially periumbilical -> radiates to RLQ
plus anorexia, n/v
describe diverticulitis pain
LLQ, constant for several days, +/- n/v
diverticulitis is mc in what pt pop
asian
lower quadrant pain w. dysuria, frequency, urgency, hematuria, f/c, CVA tenderness
pyelonephritis
mc sx of infectious colitis
diarrhea
what PE exam finding suggests appendicitis has spread to the peritoneum
mcburney point rebound tenderness
what 3 signs are associated w. appendicitis
rovsing
obturator
psoas
RLQ pain w. palpation of LLQ
rovsing sign
RLQ pain w. internal rotation of the hop
obturator sign
RLQ pain w. hip extension
psoas sign
what lab finding is suggestive of appendicitis
neutrophilia
gallstones w.in gallbladder
cholelithiasis
inflammation of the CBD, often caused by infxn or choledocholithiasis
cholangitis
inflammation of the gallbladder
cholecystitis
gallstones that have migrated from the gallbladder into the CBD
choledocholithiasis
3 lab findings suggestive of acute cholecystitis
elevated WBC
elevated alk phos
elevated bilirubin
when does pain w. cholelithasis mc occur
after eating
at night
what sign is associated w. cholelithiasis
boas - referred right subscapular pain
what are the 5 f’s of cholecystitis
female
fat
forty
fertile
fair
what sign is associated w. acute cholecystitis
murphy’s
3 sx of cholecystitis
fever
leukocytosis
jaundice
preferred initial imaging for cholecystitis
US
3 US findings of cholecystitis
gallbladder wall > 3 mm
pericholecystic fluid
gallstones
gs imaging for cholecystitis when US is inconclusive
HIDA
3 lab findings of cholecystitis
elevated alk phos
elevated GGT
elevated conjugated bilirubin
porcelain gallbladder is a complication of
chronic cholecystitis
gs imaging for choledocholithiasis
ERCP
tx for cholecystitis
cholecystectomy w.in 24-48 hr
32 yo G2P1 female, 32 weeks gestation in ED w. severe abd pain, fatigue, nausea - profound jaundice, ttp of RUQ - just returned from india
acute hepatitis
6 causes of acute hepatitis
viral hepatitides (A, B, C)
parasites (toxoplasmosis)
etoh/drugs
autoimmune hepatitis
steatohepatitis
metabolic dz
2 history clues for acute hepatitis
recent travel
sudden jaundice
prodrome of acute hepatitis
flu like symptoms
5 PE findings of acute hepatitis
RUQ pain
jaundice
slceral icterus
hepatomegaly
splenomegaly
fever
initial imaging for acute hepatitis
US
2 US findings of acute hepatitis
hepatomegaly -> most sensitive
gallbladder wall thickening
3 lab findings of acute hepatitis
elevated WBC w. atypical lymphocytes
hyperbilirubinemia
very high ALT/AST (ALT higher)
AST:ALT > 2 makes you suspect
etoh hepatitis
IgM abs indicate
early infxn
IgG abs indicate
chronic infxn
(+) IgG, (-) IgM indicates
pt is immune via prior ifxn or vaccination
4 serology markers for hepatitis B
anti HBc IgM
anti HBc IgG
HBSAg
anti HBs
(+) anti HBc IgM and HBsAg
acute HBV
(+) HBsAg
early acute HBV infxn
(+) anti HBc IgG and anti HBs
resolved acute HBV
(+) anti HBs
HBV vaccine/immunity
(+) anti HBc IgG and HBsAg
chronic HBV
2 hepatitis C serology markers
HCV RNA
anti HCV
(+) HCV RNA and anti-HCV
chronic HCV
(+) HCV RNA +/- anti HCV
acute HCV
(-) HCV RNA, (+) anti HCV
resolved HCV
when is antiviral therapy used for hepatitis
severe hep B
antiviral tx for severe hep B
nucleoside analogs: entecavir
pharm for severe alcoholic hepatitis
pentoxifylline
steroids
what is this showing
grey-turner sign
flank ecchymosis -> acute pancreatitis
what is this showing
dilation of upper duodenum
fluid in left leural cavity
pancreatitis
where does pancreatitis pain radiate
back
causes of pancreatitis
GET SMASHED
gallstones
etoh
trauma
steroids
mumps
autoimmune
scorpion sting
hypercalcemia
hyperlipidemia
ercp
drugs
imaging of choice for pancreatitis
CT
most sensitive imaging for chronic pancreatitis
ERCP
what is this showing
periumbilical ecchymosis
acute pancreatitis
ranson’s criteria for poor prognosis w. pancreatitis
at admit:
age > 55
leukocytes > 16,000
glucose > 200
LDH > 350
AST > 250
at 48 hr:
arterial PO2 < 60
HCO3 < 20
Ca < 8.0
BUN increase by 1.8+
Hct decrease by > 10%
fluid sequestration > 6 L
this is 100% one of my sacrificial lambs
complication of pancreatitis
pancreatic pseudocyst: pancreatic enzymes, blood, necrotic tissue
anal issues to know
fissure
fistula
abscess
chronic complication of anorectal abscess
anal fistula
t/f: fever is uncommon w. anal abscess
t!
sx of anal abscess
pain
swelling/erythema
painful defecation
fluctuance
tx for anal abscess
surgical drainage
warm water cleanse
analgesics
stool softener
high fiber diet
abx for high risk
open tract btw two epithelium lined areas - associated w. deeper anorectal abscesses
anorectal fistula
tx for anorectal fistula
surgery bro
tearing rectal pain and bleeding shortly after defecation, BRBPR - pain lasts several hours and subsides until next BM
anal fissure
tx for anal fissure
sitz bath
high fiber/water
stool softeners/laxatives
botox for persistent
how long do anal fissures take to heal
6 weeks
Smarty PANCE really wants us to associate anorexia w.
appendicitis
timeline of appendicitis progression
- periumbilical pain (intermittent/crampy)
- n/v
- anorexia
- pain migrates to RLQ (constant/intense)
besides appendicitis, other GI causes of anorexia
gastric/duodenal ulcers
gastric ca
lower GI bleed
gallbladder carcinoma
pancreatic carcinoma
meds
thyroid dz
epigastric pain, worse with food, vomiting, anorexia, nausea
gastric ulcers
epigastric pain, burning/aching several hr after meals, back pain, nausea, vomiting, anorexia
relieved by food
duodenal ulcers
sx of gastric cancer
weapon:
wt loss
emesis
anorexia
pain/epigastric discomfort
obstruction
nausea
hematochezia +/- pain, melena, anorexia, fatigue, syncope, SOB, shock
lower GIB
biliary colic, wt loss, anorexia, +/- cholecystitis
gallbladder carcinoma
painless jaundice, obstruction of CBD, wt loss, abd pain, back pain, weakness, pruritis, anorexia, acholic stools, dark urine, DM
pancreatic carcinoma
what sign is associated w. pancreatic carcinoma
courvoisier’s sign: enlarged, palpable gallbladder w. jaundice
what meds are associated w. anorexia
sedatives
digoxin
laxatives
thiazides
narcotics
abx
pathologic causes of constipation/obstipation
colorectal ca
bowel obstruction
volvulus
ileus
gastroparesis
what is obstipation
severe/complete constipation
consier _ in all pt’s > 50 yo w. constipation
colorectal ca
XR findings of bowel obstruction
air fluid levels
dilated loops of bowel
obstruction due to twisting/knotting of GIT - belly pain/bloating, nausea, hematochezia, constipation
volvulus
XR finding of volvulus
colonic distension
hypomobility of the GIT in absence of mechanical obstruction, absent bowel sounds
ileus
vomiting, abd pain, fullness after eating small amounts, associated w. DM
gastroparesis
causes of diarrhea
infectious
toxic
diet
GI dz
bloody diarrhea indicates (2)
invasive organism
IBD
infxn of biliary tract 2/2 obstruction - leads to biliary stasis and bacterial overgrowth
cholangitis
_ accounts for 60% of cholangitis
choledocholithiasis
besides choledocholithiasis, other causes of cholangitis
pancreatic/biliary neoplasm
post op strictures
ERCP/PTC
choledochal cysts
4 organisms associated w. cholangitis
e. coli
enterococcus
klebsiella
enterobacter
what is charcot’s triad
RUQ tenderness
jaundice
fever
cholangitis
what is reynold’s pentad
charcot’s triad
PLUS
AMS
hypotension
septic/ascending cholangitis
initial and gs imaging for cholangitis
initial: US
gs: ERCP
tx for cholangitis
stone removal (ercp)
cipro + metro
fluids
analgesia
cholecystectomy (post acute)
2 sx of primary sclerosing cholangitis
jaundice
pruritis
primary sclerosing cholangitis is associated w. what 4 diseases
IBD
cholangiocarcinoma
pancreatic ca
colorectal ca
what is primary sclerosing cholangitis
inflammation of bile ducts -> scarring -> narrowing -> liver dysfxn
2 mc cause of cirrhosis
- etoh
- hep C/B
what is the LFT ratio for cirrhosis
AST > ALT
complication of cirrhosis that occurs in 10-25% of pt’s
hepatocellular carcinoma
lab to monitor for HCC in cirrhotic pt’s
AFP
hepatic vein thrombosis is same same
budd chiari syndrome
budd chiari syndrome triad
abd pain
ascites
hepatomegaly
7 complications of cirrhosis
potal HTN
ascites
peripheral edema
esophageal varices
hepatorenal syndrome
hepatic encephalopathy
HCC
portal htn leads to (4)
ascites
peripheral edema
splenomegaly
varicosity of veins
2 causes of ascites
portal htn
hypoalbuminemia
mc complication of cirrhosis
ascites
work up for ascites
US
diagnostic paracentesis
serum albumin gradient
tx for ascites
Na restriction
furosemide/spironolactone
paracentesis
3 indications for paracentesis w. ascites
tense ascites
SOB
early satiety
5 sx of esophageal varices
dilated submucosal veins
retching
dyspepsia
hypotension
tachycardia
3 sx of hepatorenal syndrome
azotemia
oliguria
hypotension
pathology behind hepatorenal syndrome
renal hypoperfusion
pathology behind hepatic encephalopathy
ammonia accumulates -> travels to brain -> decreased mental fxn
PE findings of hepatic encephalopathy
asterixis
dysarthria
delirium
coma
what is asterixis
flapping tremor
have pt flex hands
lab finding indicative of severe cirrhosis
prolonged PT/PTT -> tx is fresh frozen plasma
skin/nail changes associated w. cirrhosis
terry’s nails
spider angiomata
palmar erythema
jaundice
slceral icterus
caput medusa
hyperpigmentation
what is this
spider angioma -> cirrhosis
what does this make you think
palmar erythema -> cirrhosis
what is this
caput medusa -> cirrhosis
what is this
terry’s nails -> cirrhosis
HCC screening recs
US q 6-12 months for pt’s w. cirrhosis
dx for HCC
CT guided bx
constipation is defined as
< 3 BM/week
rome III criteria for functional constipation
any 2 of the following x 3 months w. symptom onset 6 months prior to dx :
straining
lumpy hard stools
incomplete evacuation
digital maneuvers
sensation of obstruction/blockage
decrease in stool frequency (<3/week)
secondary causes of constipation
opioids
DM
hypothyroidism
dehydration
MS
work up for constipation should include
DRE
imaging not really recommended in geriatrics
tx for constipation
first line: bulk forming laxatives
osmotic laxatives
stimulant laxatives
stool softeners/suppositories
what are the bulk forming laxatives
psyllium seed (metamucil)
methylcellulos (citrucel)
Ca polycarbophil (FiberCon)
wheat dextrin (benefiber)
name a osmotic laxatives
polyethylene glycol (PEG)
what are the stimulant laxatives
bisacodyl
senna
sodium picosulfate
when should you do work up for constipation
after 2 weeks of refractory
infectious diarrhea assocaited w. daycare centers
rotavirus
cryptosporidium
giardia
shigella
if you see daycare center, think
rotavirus
infectious diarrhea assocaited w. composed salads (ex egg salad)
s. aureus
infectious diarrhea assocaited w. seafood/shellfish
vibrio cholerae
vibrio parahaemollyticus
infectious diarrhea associated w. raw ground beef or sprouts
e.coli 0157
infectious diarrhea associated w. poultry/pork
salmonella
infectious diarrhea associated w. undercooked beef/pork/poultry
s. aureus
clostridium perfringens
salmonella
listeria
e.coli 0157 (shiga producing)
b.cereus
yersinia
campylobacter
which pathogen is associated w. travelers diarrhea
enterotoxigenic e.coli (ETEC)
infectious diarrhea from poorly canned home foods
c perfingens
infectious diarrhea from fried rice
bacillus cereus
infectious diarrhea from raw milk
salmonella
campylobacter
e.coli 0157
listeria
infectious diarrhea associated w. camping
giardia
incubation period and sx of girardia
incubation: 1-3 weeks
sx: foul smelling, bulky stool, may wax/wane for weeks
infectious diarrhea associated w. receptive anal intercourse
HSV
chlamydia
gonorrhea
syphilis
infectious diarrhea in HIV/immuncompromised pt’s
cryptosporidium
microsporidia
isospora
CMV
mycobacterium
listeria
rice water scools
v. cholerae
bloody stools
salmonella
shigella
campylobacter
e.coli 0157
c.diff
entamoeba
yersinia
afebrile abd pain w. bloody stools
e.coli 0157
67 yo M, chronic constipation presents w. steadly LLQ pain, low grade fever, abd distension - stool guiac negative - CBC shows absolute neutrophilic leukocytosis w. left shift
diverticulitis
63 yo M w. painless BRBPR x 2 hr and LLQ pain
diverticulosis
inflammation of an abnormal pouch (diverticulum) in the intestinal wall - mc large intestines
diverticular dz
the presence of diverticulum is called
diverticulosis
inflammation of diverticulum is called
diverticulitis
mc location for diverticular dz
sigmoid colon
sx of diverticulitis
f/c
n/v
LLQ pain
dx for diverticulitis
-CT w. oral/rectal/IV contrast
-colonoscopy 1-3 months after episode
CT findings of diverticulitis (2)
fat stranding
bowel wall thickening
tx for diverticulitis
pain control
liquid diet x 2-3 days followed by high fiber diet
+/- abx
+/- US guided drainage/surgical resection
indications for colon resection w. diverticular dz
recurrent attacks
perforation
fistula
abscess
54 yo F w. odynophagia, dysphagia, retrosternal CP
esophagitis
2 types of esophagitis
non infectious
infectious
5 types of non infectious esophagitis
reflux
medication-induced
eosinophilic
radiation
corrosive
2 meds associated w. esophagitis
NSAIDs
bisposphanates
asthma sx and GERD not responsive to antacids
eosinophilic esophagitis
dx for eosinophilic esophagitis
bx
barium swallow findings of eosinophilic esophagitis
ribbed esophagus
multiple corrugated rings
4 radiosensitizing drugs associated w. esophagitis
doxorubicin
bleomycin
cyclophosphamide
cisplatin
t/f: dysphagia can lasts months after xrt therapy
t!
corrosive esophagitis is associated w.
medication attempted suicide
hallmark sign of infectious esophagitis
pain while swallowing food/liquids
pt pop mc affected by infectious esophagitis
immune compromised
pathogens associated w. infectious esophagitis
candida albicans
HSV
CMV
linear yellow-white plaques w. odynophagia or pain w. swallowing
candidal esophagitis
tx for candidal esophagitis
daily PO fluconazole
shallow punched out lesions on EGD
HSV esophagitis
tx for HSV esophagitis
acyclovir
large solitary ulcers or erosions on EGD
CMV esophagitis
tx for CMV esophagitis
ganciclovir
other pathogens associated w. infectious esophagitis
EBV
myobacterium tuberculosis
myobacterium avium
dx for infectious esophagitis
endoscopy/bx
double contrast esophagram
culture
tx for corrosive esophagitis
steroids
tx for eosinophilic esophagitis
remove triggers
ICS
3 causes of gastritis
h.pylori -> mc
inflammation of stomach lining
autoimmune or hypersensitivity
location of h.pylori gastritis
antrum
body
dx for h pylori
urea breath
fecal antigen
2 causes of inflammation related gastritis
NSAIDs
etoh
how do NSAIDs cause gastritis
they diminish local PG production in stomach and duodenum
you sould associate autoimmune/hypersensitivity gastritis w.
pernicious anemia
location of pernicious anemia related gastritis
body of fundus
triad of pernicious anemia
positive schilling test
decreased intrinsic factor
parietal cell abs
tx/dx for gastritis
- stop NSAIDs
- PPI x 4-8 weeks
- if no response -> upper GI endo w. bx and US
- test for h.pylori
triple and quadruple therapy for h. pylori
triple: clarithromycin, amoxicillin, omeprazole +/- metro
quadruple:: tetracycline, omeprazole, metro, bismuth
upper GI bleeding originates where
proximal to the ligament of treitz
vomiting of blood or coffee ground emesis
hematemesis
black tarry stool
melena
ddx for hypotn, tachycardia, abd tenderness
peptic ulcer
esophageal ulcer
mallory weiss tear
esophageal varices
malignancy
severe erosive esophagitis
emesis, retching, coughing prior to hematemesis
mallory weiss tear
odynophagia, dysphagia, retrosternal CP
severe erosive esophagitis
tx for upper GIB
NPO, IV, O2
isotonic crystalloids
IV PPI
+/- transfusion
+/- surgery
indications for transfusion: high risk vs low risk pt
high risk (elderly, CAD): Hgb < 9
low risk: Hgb < 7
passage of BRPBP
hematochezia
ddx for hematochezia
hemorrhoids
anal fissure
proctitis
polyps
colorectal ca
diverticulosis
painless bleeding w. blood on toilet paper
hemorrhoids
severe rectal pain w. defecation
anal fissure
rectal bleeding PLUS abd pain
proctitis
large volume of BRBPR
diverticulosis
what are the parasitic GI infxns
(besides my least favorite topic)
giardia
pinworm
tapeworm
hookworm
roundworm
amebiasis
schistosomiasis
diarrhea 1-3 weeks after a camping trip
waxing/waning foul smelling bulky stool
giardia
tx for giardia
1st line: tinidazole
alt: metro
perianal pruritis that is worst at night
pinworm (enterobios vermicularis)
dx for pinworm
sctoch tape test early in the AM
eggs under microscopy
tx for pinworm
mebendazole
-transmission from raw or undercooked meat
-B12 deficiency
-GI sx PLUS wt loss
tapeworm
dx for tapeworm
tape test for diphyllobothrium latum
stool sample for eggs
tx for tapeworm
praziquantel
-cough, wt loss, anemia, eosinophilia, recent travel
-larvae invade the skin -> travel to lung -> cough/swallow -> reside in intestines
hookworm
dx for hookworm
stool sample -> adult worms
tx for hookworm
mebendazole or pyrantel
mc intestinal helminth worldwide
contaminated soil
roundworm
small roundworm load can be asymptomatic, what are the sx of a large roundworm load
pancreatic duct/CBD/bowel obstruction
dx for roundworm
stool sample -> eggs vs adult worms
tx for roundworm
albendazole
mebendazole
pyrantel pamoate
-fecal/oral, contaminated water/food
-bloody diarrhea, tenesmus, abd pain, liver abscess
amebiasis (entamoeba histolytica)
dx for amebiasis
stool sample -> trophozoites
tx for amebiasis
iodoquinol or paromycin
if liver abscess: add metro
-parasitic flatworms
-aka snail fever or bilharzia
-contaminated freshwater -> penetrate skin -> migrate to liver/intestines -> rash, abd pain, bloody diarrhea, hematuria
schistosomiasis
dx for schistosomiasis
eggs in urine or feces
tx for schistosomiasis
praziquantel
when is heartburn worst
night
lying down
causes of heartburn
GERD
food intolerance
esophagitis
gastritis
hiatal hernia
PUD
heartburn frequency that indicates GERD
more than twice weekly
emergency sx of esophagitis
food stuck in esophagus
prolonged chest pain
part of. thestomach pushes up thru the diaphragm
hiatal hernia
-post prandial burning abd pain, n/v, bloating
-hx PPI/H2 blocker
-not associated w. wt loss
-hx h.pylori and/or chronic NSAIDs
PUD
who should undergo work up for heartburn
-longstanding or atypical sx: wheezing/cough/hoarseness
-refractory to max dose PPI/H2 blocker
standard work up prior to surgical antireflux procedure (4)
endoscopy w. bx
manometry
24 hr ambulatory pH testing
barium esophagography
gs dx for GERD/heartburn stuff
endoscopy w. bx
tx for zollinger ellison
PPI
tumor resection
ddx for hematemesis
PUD
esophageal varices
etoh
mallory-weiss
coagulation d.o
esophageal ca
malignany
tear in the lining of the stomach just above esophagus caused by violent retching or vomiting
mallory weiss syndrome
progressive dysphagia to solids, weight loss, reflux, hematemesis
esophageal ca
varicose veins of anus/rectum
hemorrhoids
rf for hemorrhoids
constipation/straining
pregnancy
portal HTN
obesity
prolonged sitting/standing/anal intercourse
indications for anoscopy w. hemorrhoids
BRBPR
suspected thrombosis
classifications of hemorrhoids
external
internal
sx of thrombosed hemorrhoid
significant pain
pruritis
no bleeding
purplish palpable perianal mass
what type of hemorrhoid requires excision
thrombosed external
tx for non thrombosed hemorrhoids
fiber
sitz bath
ice packs
bed rest
stool softeners
topical steroids
+/- rubber band ligation or hemorrhoidectomy
indications for rubber band ligation for hemorrhoids
protrudes w. defecation
enlargement
intermittent bleeding
indication for hemorrhoidectomy
permanently prolapsed
types of hernias
hiatal
ventral/incisional
umbilical
inguinal
you missed her didn’t you
which type of hernia is generally congenital and appears at birth
umbilical
when should you refer to surgery for umblical hernia
persists beyond 2 yo
2 types of inguinal hernias
indirect -> mc
direct
passage of intestine thru internal inguinal ring down the inguinal canal +/- to the scrotum
indirect hernia
passage of intestine thru external inguinal ring at hesselbach triangle - rarely enters scrotum
direct hernia
complications of hernias
strangulation
obstruction
incarceration
irreducible hernia that does not interfere w. blood supply to bowel
obstructed hernia/incarcerated
hernia so occluded that it can not be reduced and blood supply to bowel is impaired
strangulated
what are the 2 IBD’s
UC
Crohn’s
characteristics of UC (7)
continuous lesions
mucosal surface only
hematochezia
pus filled diarrhea
fever
tenesmus
anorexia/wt loss
barium enema findings of UC
loss of haustral markings -> lead pipe appearance
tx for UC
prednisone and masalamine
colectomy
chracteristics of crohn’s (8)
mouth to anus
transmural
skip lesions
transmural thickening
aphtous ulcers
wt loss
nonbloody diarrhea
what is this showing
cobblestoning -> crohn’s
what is this showing
lead pipe appearnce -> UC
tx for crohn’s: flares vs maintenance
flares: prednisone +/- mesalamine, metro, cipro
maintenance: mesalamine
t/f: surgery is curative for UC, but not for crohn’s
t!
continuous lesions, mucosal surface, lead pipe
UC
transmural, skip lesions, cobblestoning, fistulas and ulcers
crohn’s
24 yo M w. UC receives lomotil for excessive diarrhea -> develops fever, abd pain, tenderness
toxic megacolon
what is this showing
massively dilated colon -> toxic megacolon
toxic megacolon is mc w. which dz
UC
tx for toxic megacolon
decmpression of colon
+/- complete colonic resection
71 yo M, hx afib - sudden onset severe abd pain q 10 min after eating - normal PE except for minimal pain w, palpation - stool guaiac positive - leukocytosis w. elevated lactate, amylase, LDH
ischemic bowel dz
artery mc affected by ischemic bowel dz
superior mesenteric
hallmark of ischemic bowel dz
pain out of proportion to findings
pain w. ischemic bowel dz begins _ and is relieved by _
10-30 min after eating
relieved by lying down or squatting
gs imaging for ischemic bowel dz
mestenteric angiography
CT/XR findings of ischemic bowel dz
bowel edema
pneumotasosis intestinalis
portal venous gas
what is pneumatosis intestinalis
gas w.in the bowel
tx for ischemic bowel dz, including gold standard
bowel rest
fluids
abx
+/- resection
gs: revascularization
first sign of jaundice
scleral icterus
bilirubin > _ is a sign of jaundice related dz
2.5
causes of jaundice (lots!)
bilirubin overproduction
hemolysis
ineffective erythropoiesis
decreased hepatic bilirubin uptake
impaired conjugation
biliary tract obstruction
viral hepatitis
physiologic jaundice. ofnewborn
gilbert syndrom
dubin johnson
hemolytic jaundice is _ hepatic
obstructive jaundice is _ hepatic
hepatocellular jaundice is _ hepatic
hemolytic: pre hepatic
obstructive: post hepatic
hepatocellular: intra hepatic
-increased indirect/unconjugated bilirubin
-mild hyperbilirubinemia
-dark urine dt hemoglobinuria, dark stool
hemolytic/prehepatic jaundice
-increased direct/conjugated bilirubin
-dark urine, acholic stools
osbructive/post hepatic jaundice
causes of obstructive/post hepatic jaundice
cholestasis
biliary obstruction
lab findings associated w. obstructive/post hepatic jaundice
GGT/ALP elevated
what are acholic stools
white stools -> biliary obstruction
-increased indiret AND direct bilirubin
-dark urine
hepatocellular/intrahepatic jaundice
lab findings of hepatocellular/intrahepatic jaundice
ALT/AST markedly elevated
causes of hepatocellular jaundice
etoh hepatitis
acute hepatitis
chronic hepatitis
AST > ALT 2:1
etoh hepatitis
increased ALT and AST > 1,000
ALT > AST
acute hepatitis
increased ALT:AST but < 500
chronic hepatitis
what makes you suspect gilbert’s or dubin-johnson or hemolysis
bilirubin > 2.5 w.o increased LFTs
21 yo M brought in by gf after drinking every night last week - reports having vomited each night - tonight after vomiting he noticed blood
mallory-weiss tear
tear that occurs in the esophageal mucosa at the junction of the esophagus and stomach - caused by severe retching/vomiting and results in severe bleeding
mallory weiss tear
hx clue for mallory weiss (besides vomiting)
etoh
upper endo finding of mallory weiss
superficial longitudinal mucosal erosions
tx for mallory weiss
supportive
+/- cauterize or epi
BRBPR/hematochezia means what type of bleed
lower GI:
hemorrhoids
anal fissures
polyps
proctitis
diverticulitis
ddx for n/v
gastroenteritis
migraines
food poisoning
influenza
pyloric stenosis
PUD
hiatal hernia
common cold
infant w. projectile vomiting
pyloric stenosis
hiatal hernia sx mimic
GERD
name the anti emetics
scolpamine patch
dexamethasone
ondansetron
prochlorperazine
droperidol
GI cocktail
what are the rescue antiemetics
prochlorperazine
droperidol
what’s in a GI cocktail
maalox
visous lidocaine
droperidol
4 cardinal signs of strangulated bowel
fever
tachycardia
leukocytosis
abd tenderness
2 types of bowel obstruction
small
large
colickly abd pain, nausea, bilious vomiting, obstipation, abd distension
SBO
bowel sounds associated w. early vs late SBO
early: hyperactive
late: hypoactive
mcc of SBO
adhesions
hernias
ca
IBD
volvulus
intussusception
what is this showing
-dilated loops of bowel
-air fluid levels
little or no gas in colon
bowel obstruction
vomiting partially digested food, severe abd distension
bowel obstruction
gradually increasing abd pain w. longer intervals btw episodes of pain, abd distension, obstipation, less vomiting
large bowel obstruction
which type of bowel obstruction is more common in elderly
large
mcc of large bowel obstruction
cancer
stritures
hernias
volvulus
fecal impaction
tx for bowel obstruction
bowel rest
NGT
+/- surgery
defect in gastric or duodenal wall that extends thru the musularis mucosa into the deeper layers of the wall
PUD
gs dx for PUD
endo w. bx
tx for NSAID associated ulcers
PPI for a minimum of 8 weeks
tx for ulcers that are not due to h.pylori or NSAIDs
PPI x 4-8 weeks