Dermatology Flashcards
what is this showing
bullous pemphigoid
_ is an acquired autoimmune blistering skin d.o caused by linear deposition of abs to _ at the _ junction
bullous pemphigoid
hemidesmosomes
epidermal-dermal
more severe form of bullous pempigoid the involves the mucous membranes
pemphigus vulgaris
what is this showing
top layers of skin slip away from lower layers when rubbed -> nikolsky sign
positive nikolsky sign is associated w. which blistering skin d.o
pemphigus vulgaris
where are bullae located w. bullous pemphigoid (4)
axillae
thighs
groin
abdomen
dx for bullous pemphigoid
hallmark findings
dx: skin bx w. immunofluourescence
findings: deposition of IgG and C3 basement membrane
pruritit scalp, body, or groin
small white specs on hair shaft
lice
ovoid grayish-white eggs
nits
management of lice
-launder fomites in H2O > 131 degrees
-topical permethrin w. wet combing, repeat in 9 days
-permethrin to body, leave on 8-12 hr
-STI screen if pubic
-eyelashes: ophthalmic petroleum jelly
-severe: oral ivermectin
-treat whole fam
rule of 9’s for burns
vs
palmar method
degrees of burns
1st: sunburn - blanches w. pressure, +- tender skin
2nd: partial thickness - red/blistered, very tender skin
3rd: full thikness - tough/leathery, non tender skin
4th: into bone and muscle
minor vs major burn criteria
minor:
adults: <10% TBSA
kids/old: < 5% TBSA
< 2% full thickness
major:
adults: > 25% TBSA
kids/old: > 20% TBSA
> 10% full thickness
indications for IVF for burns
IVF of choice
children: > 10%
adults: > 15%
LR IV x 24 hr
what is this showing
pilonidal cyst: abnl hairgrowth at tailbone containing hair/skin
pilonodial cysts result from
abscess -> sinus tract at upper part of natal cleft
teenager w. intermittent pain, discomfort, and swelling above the anus or near tailbone
pilonidal cyst
tx for pilonidal cyst
I&D/remove
find sinus tract
cefazolin + metro/augmentin if cellulitis
acute bacterial skin/skin structure infxn involving dermis and subcutaneous tissue
cellulitis
classic sx of cellulitis
pain
erythema
warmth
swelling
describe skin findings of cellulitis
flat margins, not well demarcated
mc cause of cellulitis in kid vs adults
kids: h.flu, strep pneumo
adults: staph, strep
dx for cellulitis
culture all purulent wounds
tx for cellulitis:
MSSA:
MRSA:
animal bite:
puncture wound:
MSSA: cephalexin vs dicloxacillin
animal bite: augmentin
puncture wound: cipro (think pseudo)
MRSA: bactrim vs clinda vs doxy vs vanco/linezolid
2 areas mc affected by pressure sores
sarum
hip
stages of pressure ulcers
stage 1: localized erythema, no blanching, bony surface
stage 2: partial loss of dermal layer, pink ulceration
stage 3: full dermal loss, subcutaneous fat often exposed
stage 4: full thickness ulceration exposing bone/tendon/muscle
common complication of pressure sore
osteomyelitis
tx for pressure ulcers
stage I: aggressive preventive, thin film dressings
stageII: occlusive dressing, transparent films, hydrocolloids
stage III-IV: debridement, calcium alginate dressing, hydrocolloids, occlusive dressings, +/- debridement
5 rf for pressure ulcers
> 65 yo
impaired circulation
immobilizatoin
malnutrition
incontinence
what stage pressure ulcer is this
I
what stage ulcer is this
III
what stage ulcer is this
II
what stage ulcer is this
IV
4 types of dermatitis to know
contact
atopic
seborrheic
perioral
2 types of contact dermatitis
allergic
irritant
what is this showing
well demarcated erythema, erosions, vesicles -> contact dermatitis
2 common causes of allergic dermatitis
what type of hypersensitivity is it
nickel
poison ivy
type IV
5 causes of irritant dermatitis
diaper rash
cleaners
solvents
detergents
urine
feces
tx for contact dermatitis
burow’s solution (aluminum acetate)
topical steroids
zinc oxide
zinc oxide makes you think of
tx for diaper rash
what is this showing
pruritic, eczematous lesions, xerosis, lichenification -> **atopic dermatitis **
mc location of atopic dermatitis: adolescents vs infants
adolescents: flexor creases -> ex antecubital and popliteal folds
infants: face, scalp
atopic dermatitis is a type _ hypersensitivity
1
rapidly evolving red rash, may be blistered or swollen
eczema
what is this showing
nummular eczema
first line tx for eczema
topical steroids
erythematous yellowish greasy scales - crusted lesions
seborrheic dermatitis (cradle cap)
mc location for seborrheic dermatitis: infants vs adults/adolescents
infants: scalp
adults/adolescents: body folds
tx for seborrheic dermatitis
ketoconazole shampoo/topical
what is this showing
papulopustular plaques/scales around the mouth -> perioral dermatitis
what pt pop does perioral dermatitis mc affect
what is the tx
young women
topical metronidazole
tx to avoid for perioral dermatitis
steroids
classification of rashes
infectious vs noninfectious
noninfectious rashes to know
eczema
contact dermatitis
psoriasis
seborrheic dermatitis
drug eruptions
rosacea
hives (utircaria)
allergic dermatitis
xerosis (dry skin)
erythematous, morbilliform, maculopapular rash starting on head and spreading downward
measles
5 causes of breast discharge
mastitis/breast abscess
breast cancer
gynecomastia
inflammatory breast cancer
hypogonadism
nipple discharge, breast enlargement, overweight
gynecomastia
nipple discharge, sexual dysfxn, reduced sex drive
hypogonadism
what mite causes scabies
sarcoptes scabiei
what rash is associated w. scabies
pruritic papules
s shaped/linear burrows on the skin
worse at night
severely itchy
where is scabies commonly located
web spaces of hands, wrists, waist
definitive dx for scabies
microscopic eval of skin scrape
tx for scabies
topical permethrin 5% to entire body -> wash off after 8-14 hr
repeat in one week
wash all fomites in high heat, no contact w. body x 72 hr
alt/severe: oral ivermectin
mc adverse drug rxn
skin
derm sx of impending CVD
-anaphylaxis
-DRESS (drug rash w. eosinophilia/systemic sx)
-SJS/TEN
-extensive bullous rxn
-generalized erythroderma
tx for anaphylaxis or widespread urticaria
epinephrine
prednisone
antihistamines
what is this showing
drug rxn
2 spider bites to know
brown recluse
black widow
what spider is this
brown violin on the abdomen -> brown recluse
ps this is my least favorite flashcard of all time
what spider is this
red hourglass on abdomen -> black widow
ps this is tied for my least favorite flashcard of all time
brown recluse bites are assocaited w. _ symptoms
black widow bites are associated w. _ symptoms
brown recluse: skin necrosis
black widow: neurologic
skin sx of brown recluse bite
first 3-4 hr: local burning, central necrosis, erythematous margin around ischemic center halo
24-72 hr: hemorrhagic bullae w. eschar formation -> necrosis
tx for brown recluse bite
wound care
local symptomatic measures
delayed excision
neuro manifestations of black widow bite
n/v
Ha
fever
syncope
convulsions
+/- rxn at bite site
tx for black widow bite
wound care
local symptomatic measures
+/- opioids/benzos
anti-venom in kids/elderly
what is this showing
large, confluent, erythematous plaques
bullae near jaw
erysipelas
well-demarcated, raised, superficial skin infxn w. lymphatic involvement
erysipelas
erysipelas is always caused by
GAS (pyogenes)
systemic sx of erysipelas
f/c
dx and tx for erysipelas
dx: C&S
tx:
-mild: pen g
-moderate: bactrim + pcn/cephalexin
-severe: carbapenems + linezolid OR vanco
severe hypersensitivity complex affecting skin and mucus membranes
SJS
progression of SJS
- flu like prodrome
- painful red/purplish rash that spreads and blisters
- layers of skin peel away in sheets -> Nikolsly sign
more severe form of SJS
toxic epidermal necrolysis (TEN)
SJS affects _% of the body
TEN affects _% of the body
SJS: 3-10%
TEN: >30%
dx for SJS/TEN
skin bx showing necrotic epithelium
tx for SJS/TEN
early admit to burn unit
lytes/fluids/nutrition
ABC
eye care
IVIG
_ may increase risk of sepsis in SJS/TEN
steroids
what is this showing
SJS
what is this showing
TEN
zoster presentation: primary vs later
primary: vesicles on an erythematous base
later: dewdrops on a rose petal
herpes zoster starts on the _ and spreads down
face
how is zoster transmitted
respiratory droplets
after manifesting as chicken pox, zoster remains latent in the
dorsal root ganglion
what is this showing
shingles
definitive dx for zoster
tzanck smear -> multinucleated giant cells
shingles involving CN V
zoster opthalmics
what is this showing
dendritic lesions on slit lamp exam -> zoster opthalmicus
zoster involving CN VII -> otalgia, lesions on the ear, auditory canal, and TM - facial palsy auditory sx
zoster oticus -> ramsay hunt syndrome
tx for shingles
acyclovir vs valacyclovir vs famciclovir
w.in 72 hr to prevent post herpetic neuralgia
what is post herpetic neuralgia
pain > 3 mo
paresthesias
decreased sensation
tx for postherpetic neuraltia (3)
gabapentin vs TCA
topical lidocaine
capsaicin
when is the zoster vaccination recommended
50 and older
2 doses 2-6 months apart
crusting facial lesions
red rash w. golden “honey-colored crust”
impetigo
2 pathogens associated w. impetigo
s. aureus - mc
GABHS
progression of impetigo
- papules -> vesicles w. surrounding erythema
- vesicles rupture -> form thick adherent, golden crust
_ is a common finding w. impetigo rash
LAD
mc age for impetigo
2-5
where do impetigo sores mc start
nose/mouth
4 hallmarks of impetigo
nonpainful
pruritic
honey colored
weeping
4 rf for impetigo
warm humid climate
poverty
crowding
poor hygiene
what is secondary impetigo
forms at site of abrasion/scratches
dx for impetigo
gram stain w. culture
tx for impetigo
mild: topical mupirocin
severe: dicloxacillin vs cephalexin
MRSA: doxy, clinda, bactrim
when can kids return to school after starting abx for impetigo
24 hr
complication of impetigo
post strep GN
skin rash triggered by rxn to foods, meds, stress, or irritants
urticaria
describe urticaria
blanchable, pruritic, raised, red or skin colored papules, wheels, plaques
disappear w.in 24 hr
localized urticaria appearing where the skin is rubbed (histamine release_
darier’s sign
painless, deeper form of urticaria affecting lips, tongue, eyelids, hands, genitals
angioedema
what are the different types of antihistamines
-
H1 blockers:
-first gen: hydroxyzine, diphenhydramine
-second gen: allegra, claritin, clarinex, zyrtec - H2 blockers: cimetidine, ranitidine
first gen antihistamines (hydroxyzine, diphenydramine) are mc used to treat
insomnia
anxiety
second gen antihistamines (allegra, claritin, clarinex, zyrtec) are mc used to treat
skin conditions
what is this showing
uticaria/hives
4 systemic d.o that cause itching
allergies
liver dz/jaundice
CKD
psychogenic
5 viral exanthems to know
erythema infectiosum (fifth dz/parvo)
hand-foot-mouth dz
measles
rubella
roseola (sixth dz)
what is this showing
“slapped cheek rash”
erythema infectiousum/parvo/5th dz
what is this showing
lacy, reticular rash -> erythema infectiosum/parvo/5th dz
what pathogen causes hand-foot-mouth dz
coxsackievirus type A
what is this showing
hand-foot-mouth dz
cough
coryza
conjunctivitis
cephalocaudal spread
4 c’s of measles
describe the rash associated w. measles
morbilliform, maculopapular brick red rash beginning on face, progressing to palms/soles
what is this
measles
what is this showing
koplik spots -> precedes measles
describe koplik spots
small red spots in buccal mucosa w. blue-white pale center
tx for measles
supportive
antiinflammatories
isolation x 1 week after rash onset
rubella rash first appears on the _ face
and has _ spread
face
cephalocaudal spread
major risk w. rubella
teratogenic in 1st trimester -> deafness, cataracts, TTP, mental retardation
roseola (6th dz) is caused by
HSV 6 or 7
only childhood exanthem that begins on the trunk and spreads to the face
roseola
progression of roseola (6th dz)
- high fever prodrome x 3-5 days
- rose pink maculopapular blanchable rash on trunk/back and face