GI Medications Flashcards
Misoprostol (Cytotec)
Gastric Protectant
Suppresses gastric acid secretion, prevents ulcers from NSAIDs
Sucralfate (Carafate)
Gastric Protectant
Creates protective barrier from acid and pepsin
*Give on empty stomach
Pirenzepine (Gastrozepine)
Muscarinic Antagonist. Suppresses gastric acid secretion
Histamine 2 (H2)-Receptor Antagonists
Suppresses gastric acid secretion
- Alleviates symptoms of heartburn - Prevents stress ulcers - Promotes healing in GERD
Cimetidine (Tagamet)
Histamine 2 (H2)-Receptor Antagonists
Suppresses gastric acid secretion
- Alleviates symptoms of heartburn - Prevents stress ulcers - Promotes healing in GERD
Side effects: Confusion
Ranitidine (Zantac)
Histamine 2 (H2)-Receptor Antagonists
Suppresses gastric acid secretion
- Alleviates symptoms of heartburn - Prevents stress ulcers - Promotes healing in GERD
Famotidine (Pepcid)
Histamine 2 (H2)-Receptor Antagonists
Suppresses gastric acid secretion
- Alleviates symptoms of heartburn - Prevents stress ulcers - Promotes healing in GERD
Nizatidine (Axid)
Histamine 2 (H2)-Receptor Antagonists
Suppresses gastric acid secretion
- Alleviates symptoms of heartburn - Prevents stress ulcers - Promotes healing in GERD
Proton Pump Inhibitors
Suppress gastric acid secretion
-Treats active ulcer disease, erosive esophagitis
Esomeprazole (Nexium)
Proton Pump Inhibitor
Suppress gastric acid secretion
-Treats active ulcer disease, erosive esophagitis
Lansoprazole (Prevacid)
Proton Pump Inhibitor
Suppress gastric acid secretion
-Treats active ulcer disease, erosive esophagitis
Omeprazole (Prilosec)
Proton Pump Inhibitor
Suppress gastric acid secretion
-Treats active ulcer disease, erosive esophagitis
Pantoprazole (Protonix)
Proton Pump Inhibitor
Suppress gastric acid secretion
-Treats active ulcer disease, erosive esophagitis
Raberprazole (Aciphex)
Proton Pump Inhibitor
Suppress gastric acid secretion
-Treats active ulcer disease, erosive esophagitis
Medication Regimen for Treating H. pylori infections
Antibiotics and PPI. Purpose is to protect the ulcer and kill the bacteria.
Triple Therapy
-Esomeprazole (Nexium), Amoxicillin (Amoxil), Clarithromycin (Biaxin)
or
Quadruple Therapies
- Esomeprazole (Nexium), Metronidazole (Flagyl), tetracycline, bismuth subsalicylate - Ranitidine (Zantac), Metronidazole (Flagyl), tetracycline, bismuth subsalicylate
Metoclopramide (Reglan)
Prokinetic Agent. Increases gastric emptying. Used to treat gastric reflux, vomiting, and paralytic ileus.
*Contraindicated in obstruction, hemorrhage, or perforation
Bile Acid Sequestrants
Helps rid body of bile salts through the feces.
-Treats hypercholesterolemia, biliary obstruction, pruritus associated with biliary disease
*Note: Can worsen suspected bowel obstruction or severe constipation
Colesevelam (Welchol)
Bile Acid Sequestrant
Helps rid body of bile salts through the feces.
-Treats hypercholesterolemia, biliary obstruction, pruritus associated with biliary disease
*Note: Can worsen suspected bowel obstruction or severe constipation