GI drugs

Question 1

omeprazole

Answer 1

• drug class: PPI
• common indications: GORD, PUD
• mechanism of action: inhibit the proton pumps in the parietal cells in the stomach and so decrease acid production
• common side effects: gi effects, headaches, dizziness, drowsiness
• uncommon side effects:
• drug-drug interactions: cyp inhibitor - dec clopidogrel action, inc warfarin and heparin action
• contra-indications: osteoporosis (inc fracture risk)