GI Cells Flashcards

1
Q

Where is the portal triad of each lobule located?

A

In the corner of the lobule

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2
Q

What is on either side of hepatocytes?

A

Sinusoids

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3
Q

What is at the centre of the lobule?

A

The Central vein

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4
Q

How are liver lobules arranged?

A

Hexagonally

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5
Q

Why do patients with liver failure bleed easily?

A

The liver produces clotting factors, which is impaired by liver failure

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6
Q

What does high GGT paired with abnormal clotting time indicate?

A

Alcohol related liver disease

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7
Q

What do fat depositions in the liver look like under a microscope?

A

Big, empty white spaces

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8
Q

What cells line blood vessels?

A

Endothelial cells

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9
Q

What cells line bile ducts?

A

Epithelial cells

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10
Q

How do blood vessels appear under the microscope?

A

White spaces with red specks (blood vessels) in them

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11
Q

How do immune cells appear?

A

Purple specks, smaller than nuclei

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12
Q

Name two drugs that cause liver damage

A

Methotrexate and Paracetamol

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13
Q

What immune cells are present in chronic inflammation?

A

Lymphocytes

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14
Q

What does the presence of iron in the liver mean?

A

Patient suffers from haemochromatosis

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15
Q

What tissue is squamous epithelium present in?

A

Any tissue exposed to the outside environment (e.g oesophagus)

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16
Q

Why do alcoholics get acid reflux?

A

Oesophageal sphincter is relaxed

17
Q

What kind of cells replace the normal cells of the oesophagus in Barret’s oesophagus?

A

Intestinal epithelium (goblet cells)

18
Q

How do signet cells appear?

A

White space in centre (usually mucin) which pushes nucleus to the side