Formative Assessment

Question 1

How many units of alcohol are in a standard glass of wine (175ml)?

Answer 1

2 units of alcohol

Question 2

What is AST short for?

Answer 2

Aspartate aminotransferase

Question 3

What is the Ligamentum teres within the falciform ligament formed from?

Answer 3

Umbilical vein

Question 4

What is portal hypertension mostly associated with?

Answer 4

Splenomegaly

Question 5

What is acute pancreatitis associated with?

Answer 5

Steroid use

Question 6

Where is Alk Phos not found?

Answer 6

The lung

Question 7

What may result from persistent vomiting?

Answer 7

Metabolic alkalosis

Question 8

Where are hepatocytes not found in the liver?

Answer 8

The portal tract

Question 9

What substance is bilirubin produced from in a normal metabolic pathway?

Answer 9

Biliverdin

Question 10

What kind of shock will a patient with haematemesis suffer from?

Answer 10

Hypovolaemic shock

Question 11

What is the liver derived from embryologically?

Answer 11

The foregut

Question 12

How is glucose produced once the glycogen stores in the liver have been used?

Answer 12

Gluconeogenesis

Question 13

Where is the respiratory centre of the brain located?

Answer 13

The brainstem

Question 14

What confers the strongest risk for hepatocellular carcinoma?

Answer 14

Alcohol

Question 15

What is ALT short for?

Answer 15

Alanine aminotransferase

Question 16

Why do women become intoxicated faster than men?

Answer 16

They have less alcohol dehydrogenase and a higher percentage of body fat

Question 17

What effect do water, caffeine and glucose have on alcohol elimination?

Answer 17

Absolutely none

Question 18

What cardiomyopathy is associated with chronic alcoholism?

Answer 18

Dilated cardiomyopathy

Question 19

Which clotting factor is not made in the liver?

Answer 19

Clotting factor VIII

Question 20

How many segments is the liver divided into?

Answer 20

8 segments

Question 21

What are treatments intended to manage ascites in cirrhosis aimed at?

Answer 21

Reducing sodium levels

Question 22

What is alcohol known to increase the precipitation of?

Answer 22

Uric acid

Question 23

What does the term inotrope refer to?

Answer 23

Cardiac contractility

Question 24

What syndrome is severe alcoholic hepatitis associated with?

Answer 24

Hepatorenal syndrome

Question 25

What cells is fibrosis/cirrhosis of the liver mediated by?

Answer 25

Hepatic stellate cells/interstitial cells of Ito

Question 26

How does Antabuse work?

Answer 26

Inhibits aldehyde dehydrogenase

Question 27

How is Dupuytren's contracture caused?

Answer 27

Scarring of the palmar fascia

Question 28

What is the legal age for drinking alcohol at home whilst supervised?

Answer 28

5 years old

Question 29

Which nerve supplies the heart?

Answer 29

The vagus nerve

Question 30

What is a patient with normal GGT, AST and ALT but high Alk Phos likely to have?

Answer 30

Bone disease

Question 31

What is alcohol initially metabolised by?

Answer 31

Alcohol dehydrogenase

Question 32

What is jaundice as a result of alcoholic hepatitis caused by?

Answer 32

Conjugated bilirubin

Question 33

What is thiamine deficiency associated with?

Answer 33

Wernicke-Korsakoff Syndrome

Question 34

Why does alcohol cause diuresis?

Answer 34

It decreases ADH levels

Question 35

What biochem test is most useful for assessing synthetic liver function in a patient with an upper GI bleed?

Answer 35

Prothrombin time

Question 36

What is the definition of binge drinking?

Answer 36

>8 units/day for men and women

Question 37

What drug is used for medically assisted alcohol withdrawl?

Answer 37

Chlorodiazepoxide

Question 38

What is the abnormal gait associated with Wernicke-Korsakoff syndrome called?

Answer 38

Ataxic gait

Question 39

What drug causes a faster rate of alcohol absorption?

Answer 39

Domperidone

Question 40

What is the cause of facial flushing and feeling unwell?

Answer 40

Aldehyde

Question 41

How many units are in a 70cl bottle of 40% alcohol?

Answer 41

28 units

Question 42

What is measured to assess perfusion in a patient with a severe GI bleed?

Answer 42

Lactate

Question 43

How many calories are in 1g of alcohol?

Answer 43

7kcal

Question 44

Is narrowing repertoire a recognised feature of dependence syndrome as per ICD-10?

Answer 44

No

Question 45

What is the usual timescale for the development of delirium tremens?

Answer 45

3-10 days

Question 46

What is the safe limit for drinking during pregnancy as per the UK Chief Medical Officer?

Answer 46

None-there is no safe level

Question 47

According to the World Cancer Research Fund, there is a strong association between drinking alcohol and which cancer?

Answer 47

Breast cancer

Question 48

What is listed under part 2 of the death certificate?

Answer 48

Conditions contributing but not directly responsible for death

Question 49

What is sometimes used to treat patients with an osmol gap?

Answer 49

Ethanol (used to treat methanol poisoning)

Question 50

How many units of alcohol are in a 1l premium bottle of cider (8%)?

Answer 50

10 units

Question 51

What are caput medusae not associated with?

Answer 51

Acute pancreatitis