GI Cancer Flashcards
1
Q
What are the two types of oesophageal cancer?
A
Adenocarcinoma
Squamous cell carcinoma
2
Q
How does adenocarcinoma arise?
A
Metaplastic columnar cells
Lower 3rd of oeso
Acid reflux
More de world
3
Q
How does squamous cell carcinoma arise?
A
Normal oesophageal squamous epithelium
Upper two 3rd
Less dev world
4
Q
Describe progression from reflux to cancer
A
Oesophagitis
Barrett’s - metaplasia
DYSPLASIA
CARCINOMA
5
Q
What is the pathilogy of colorectal cancer?
A
Not simple mendelian inheritance
- unless FAP
Sequence of genetic errors
- combo
6
Q
Symptoms of colorectal cancer
A
Change in bowel habit
- Diarrhoea
- Constipation
Bloody stool
7
Q
Diagnostic methods?
A
X-ray CT Barium enema Colonoscopy CT virtual colonoscopy
