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Pharmacology > GI > Flashcards

GI Flashcards

1
Q

Omeprazole

A

PPI

> parietal cell canaliculus (HKATPase)

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2
Q

Cimetidine

A

H2RA
H2R: parietal cell
v cAMP > v => H+
(+ PKA, - gastrin / ACh

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3
Q

Amoxicillin

A

H pylori ABX

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4
Q

Calcium carbonate

A

Antacid

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5
Q

Aluminium hydroxide

A

Antacid

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6
Q

Clarithromycin

A

H pylori ABX

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7
Q

Magnesium hydroxide

A

Antacid

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8
Q

Sodium hydroxide

A

Antacid

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9
Q

Misoprostol

A

Prostaglandin analogue

Parietal PGE2

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10
Q

Codeine

A

Opioid receptor antagonist

U/D receptors: myenteric plexus

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11
Q

Movicol

A

Osmotic laxative
LB
(= macrogols)

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12
Q

Glycerin

A

Stimulant laxative

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13
Q

Docusate sodium

A

Stimulant laxative

Gut

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14
Q

Lactulose

A

Osmotic Laxative

LB

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15
Q

Morphine

A

Opioid receptor antagonist

U/D receptors of myenteric plexus

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16
Q

Loperamide

A

Opioid receptor antagonist

U receptors in myenteric plexus

17
Q

Ispaghula husk

A

Bulk forming laxative

18
Q

Methyl cellulose

A

Bulk forming laxative

19
Q

Aprepitant

A

Neurokinin 1 receptor antagonist

5HT3 receptor, CTZ

20
Q

Hyoscine hydrobromide

A

M receptor antagonist

Vestibular nuclei

21
Q

Fosaprepitant

A

NK1 receptor antagonist

22
Q

Netupitant

A

NK1 RA

5HT3, CTZ

23
Q

Cyclizine

A

H1 Receptor antagonist

Vestibular nuclei

24
Q

Ondasteron

A

5HT3RA

visceral afferents

25
Q

Promethazine

A

H1RA

Vestibular nuclei

26
Q

Cinnirazine

A

H1RA

vestibular nuclei

27
Q

Prochlorperazine

A

D2RA

Visceral afferents

28
Q

Metoclopramide

A

D2RA

Visceral afferents

29
Q

Domperidone

A

D2RA

visceral afferents

30
Q

Haloperidol

A

D2RA

Visceral afferents

31
Q

Dexamethasone

A

Corticosteroids

CTZ / D2R

32
Q

Nabilone

A

Cannabinoids

CTZ

33
Q

Methylprednisolone

A

Corticosteroids

CTZ / D2R

34
Q

Benzodiazepine

A

GABA receptor antagonist

CTZ / 5HT3

35
Q

Mirtazepine

A

5HT3 (TCA)

36
Q

Gabapentin

A

GABA mimic

^5HT3

37
Q

Cisapride

A

Prokinetic

LOS / Pylorus

38
Q

Midazolam

A 
CTZ / 5HT3 
GABA receptors (v => 5HT3)

Pharmacology (12 decks)

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