CYP Enzyme metabolism Flashcards
1
Q
sulphonamides
A
N-acetyltransferase
hypersensitivity
2
Q
omeprazole
A
CYP 2C19
3
Q
isoniazid
A
N-acetyltransferase
SLE
4
Q
TCA
A
CYP 2D6
confusion
5
Q
B blocker
A
CYP 2D6
bradycardia
6
Q
azathioprine
A
TPMT
myelotoxicity
7
Q
losartan
A
CYP 2C9
v BP
8
Q
diazepam
A
CYP 2C19
sedation
9
Q
Warfarin
A
CYP 2C9
haemorrhage
10
Q
phenytoin
A
CYP 2C9
toxicity
11
Q
tolbutamide
A
CYP 2C9
hypoglycaemia
12
Q
procainamide
A
N-acetyltransferase
SLE
13
Q
opioids
A
CYP 2D6
addiction / dependance
14
Q
5 florouracil
A
Dihydropyrimidine dehydrogenase
myelotoxicity
15
Q
Anti psychotics
A
CYP 1A2
dyskinesia