CYP Enzyme metabolism Flashcards

1
Q

sulphonamides

A

N-acetyltransferase

hypersensitivity

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2
Q

omeprazole

A

CYP 2C19

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3
Q

isoniazid

A

N-acetyltransferase

SLE

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4
Q

TCA

A

CYP 2D6

confusion

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5
Q

B blocker

A

CYP 2D6

bradycardia

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6
Q

azathioprine

A

TPMT

myelotoxicity

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7
Q

losartan

A

CYP 2C9

v BP

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8
Q

diazepam

A

CYP 2C19

sedation

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9
Q

Warfarin

A

CYP 2C9

haemorrhage

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10
Q

phenytoin

A

CYP 2C9

toxicity

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11
Q

tolbutamide

A

CYP 2C9

hypoglycaemia

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12
Q

procainamide

A

N-acetyltransferase

SLE

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13
Q

opioids

A

CYP 2D6

addiction / dependance

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14
Q

5 florouracil

A

Dihydropyrimidine dehydrogenase

myelotoxicity

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15
Q

Anti psychotics

A

CYP 1A2

dyskinesia

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16
Q

statins

A

CYP 3A4