GI Flashcards

1
Q

what do parietal cells release?

A

HCl acid

intrinsic factor

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2
Q

what do chief cells release?

A

pepsin

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3
Q

what do G cells release?

A

Gastrin

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4
Q

secretin in released by what part fo the intestines?

A

duodenum (it inhibits gastric production and signals the pancreas to release bicarb)

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5
Q

gold standard test for GERD?

A

24h ambulatory pH monitoring

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6
Q

gold standard test for achalasia

A

esophageal manometry

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7
Q

tx of choice for active esophageal varices

A

endoscopic ligation

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8
Q

meds used in esophageal varices

A

octreotide, vasopressin

PPI, Abx

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9
Q

what can be used for esophageal varices if bleeding cannot be controlled with endoscopic interventions or medications?

A

balloon tamponade

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10
Q

Side effect of TIPS procedure

A

encephalopathy

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11
Q

gold standard dx for gastritis and PUD

A

endoscopy

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12
Q

gold standard for H pylori testing

A

endoscopy w/ bx

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13
Q

best screening test for zollinger ellison syndrome

A

fasting gastrin level

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14
Q

what inhibition test is performed with zollinger ellison syndrome?

A

secretin

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15
Q

hereditary conjugated hyperbilirubinemia d/t decreased hepatocyte excretion of conjugated bilirubin

Pt will have grossly black liver on bx

A

dubin-johnson syndrome

Dublin, direct, dark

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16
Q

hereditary unconjugated hyperbilirubinemia with normal LFT

A
crigler-najjar syndrome 
Gilbert syndrome (more common)
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17
Q

what is the inital test and the gold standard test for acute cholecystitis

A

U/S

HIDA

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18
Q

MC cause of fulminant hepatitis

A

acetaminophen

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19
Q

what are sxs of fulminant liver dz

A
encephalopathy 
coagulopathy
jaundice
asterixis
ascites
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20
Q

what hepatits viruses are fecal-oral

A

A E

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21
Q

IV drug users are at risk of developing what hepatits infxn

A

C

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22
Q

what does hep D need to cuase infection

A

HepB

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23
Q

Hep B medications?

A
alpha-interferon 2b
lamivudine
adefovir
tenofovir
entecavir
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24
Q

hepatic venous outflow obstruction

A

budd-chiari syndrome (hepatic vein obstruction)

25
how do you dx and tx budd-chiari syndrome
U/S shunts, balloon angioplasty w/ stent, anticoagulation
26
what tumor marker is used to track hepatocellular carcinoma?
alpha-fetoprotein
27
what is cholestyramine used for?
pruritis d/t increased levels of bile salts
28
idiopathic autoimmune d/o of intrahepatic small bile ducts Associated with anti mitochondrial antibody usually incidental finding with high alkaline phosphate
Primary biliary cirrhosis
29
Tx for Primary biliary cirrhosis
urodeoxycholic acid (reduce progression)
30
autoimmune progressive cholestasis, diffuse fibrosis of intrahepatic and extrahepatic ducts associated with UC
primary sclerosing cholangitis
31
tx for primary sclerosing cholangitis
transplant, stenting to relieve sxs
32
autosomal recessive copper accumulation in liver, brain, kidney, cornea
wilsons dz
33
tx for wilsons dz
D-pencillamine (chelates copper) | zinc + ammonium tetrathiomolybdate (enhance fecal excretion)
34
mc cause of small bowel obstructions | large bowel?
adhesions | obstruction
35
test of choice to dx lactose intolerance
hydrogen breath test
36
abx used in diverticulitis
cipro/bactrim + metronidazole
37
dx for UC vs crohns
``` UC = felx sig Crohns = upper GI series with small bowel follow through ```
38
how should colon CA screening be performed for..... 1. average risk 2. 1st degree relative >60y 3. 1st degree realtive <60y 4, lynch 5, FAP
1. @50 fecal occult = annual, colonoscopy = e 10 2. @40 fecal occult = annual, colonoscopy = e 10 3. @40 (or 10 yrs prior) fecal occult = annual, colonoscopy = e 5 yrs 4, @ 20-25, colonoscopy q 1-2 yrs 5. @10-12, felx sig
39
deficiency associated with loss of night vision, imparied immunity, bitot's spots (white spots on conjunctiva d/t squamous metaplasia)
Vitamin A
40
hyperkeratotic follicular papules Hemorrhage (gums, skin, joints) Hematologic (anemia, glossitis)
Scurvy (Vit C, ascorbic acid)
41
softening of the bones with bowing and rachitic rosary in children looser lines for adults
vitamin D Rickets (children) osteomalacia (adults)
42
ETOH mc cause wernickes beriberi (nervous system changes or HF)
Thiamine (B1) | one drunk man
43
oral-ocular-genital syndrome oral (magenta tongue, lesions) ocular (photophobia, corneal lesions) Genital (scrotal dermatitis)
Riboflavin (B2) | 2 nuts are involved
44
diarrhea, dementia, dermatitis | high corn diet
Niacin (B3) | 3 D's
45
chronic ETOH, peripheral neuropathy, sz HA.
Pyridoxine (B6)
46
parasthesias, gait abnormalities, memory loss, macrocytic anemia
cobalamin B 12
47
short incubation ate dairy products, mayonnaise, meats or eggs prominent V, abd cramps, HA, D
staph aureus
48
similar to staph Contaminated foods Vomiting, cramps D
Bacillus cereus
49
rice water stools raw shellfish Tx?
vibrio cholerae fluids! tetracyclines
50
travelers D unsanitary drinking water Tx?
enterotoxigenic e coli fluids! FQ
51
strinkingly high lymphocytes, pseudomembranoue colitis Tx?
C. diff metronidazole vanc PO
52
can lead to guillain barre syndrome undercooked poultry gram negative S, comma, seagull shaped tx?
campylobacter enteritis fluids erythromycin
53
tenesmus, explosive D, mucoid/bloody D febirle szs in children Tx?
shigella Bactrim, FQ
54
sickle cell pts are at high risk of osteomylitis with this infxn pea soup stools Tx?
salmonella (typhoid fever) FQ
55
noninfectious D affects the ___ | Infectious D affects the ____
small intestine | Large intestine
56
frothy, greasy, fould smelling poo contaminated streams Tx?
Giardia lambia metronidazole
57
GI colittis, dysentery, liver abcess tx?
abebiasis metronidazole
58
farmers around contaminated soil malabsorption, rhythmic motion of eyes with chewing Tx?
whipple's dz PCN