GI 3 Flashcards
gram negative faculative anaerobe
comma curved shape
free living in water
require sodium chloride for growth
vibrio spp.
severe watery diarrhea “rice water”
vibrio cholerae
immunity to cholera
associated to the O antigen
cholera pathogenesis
toxin co-regulated pilus and AB cholera toxin which activates adenylate cylcase –> diarrhea without cell damage
treatment of cholera
rehydration therapy IV and oral
explosive watery diarrhea, nasuea, vomiting, abdominal cramps, low grade fever
vibrio parahaemolyticus
virulence of vibrio parahaemolyticus
kanagawa hemolysin (induces chloride secretion thus watery diarrhea)
associated with consumption of raw shellfish
vibrio parahaemolyticus
bacterial gastroenteritis in Japan and southeast asia
vibrio parahaemolyticus
gram negative coccobacilli
- fever, abdominal cramps, watery-> bloody diarrhea
- improperly cook pork
yersinia enterocolitica
pathogenesis of yersinia enterocolitica
- binds and invade Mcells in terminal ileum
- involves T3SS and injection of Yops
- heat stable enterotoxin
gram positive anaerobe, non-invasive, spore forming
clostridium difficile
CDAD, psuedomembrane colitis, fulminant colitis with toxic megacolon
associated with hospitals
clostridium difficile
pathogenesis clostridium difficile
toxin AB disrupts host cell cytoskeleton –> diarrhea
treatment clostridium difficile
oral vancomycin or metronidazole