G3 turning point key points

Question 1

gram negative
white colonies on macConkey agar
negative H2S

• 3 yo diarrhea, fever, chills

Answer 1

shigella sonneii

Question 2

• rare hamburgers

- malaise, ambdominal cramps and bloody diarrhea

Answer 2

EHEC

Question 3

EHEC toxin mechanism

Answer 3

(shiga-like toxin) blocking translation by cleaving a subunit of the 60S ribosome

Question 4

activation of adenylate cyclase leading to activation of cAMP

Answer 4

cholera toxin

LT toxin of ETEC

Question 5

activation of guanylate cyclase leading to increased cGMP

Answer 5

ST toxin of ETEC

Question 6

blocking translation by cleaving a subunit of the 60S ribosome

Answer 6

shiga-like toxin

Question 7

disruption of the host cell cytoskeleton

Answer 7

shigella toxin

c. difficile

Question 8

blocking of Ach release at the NMJ

Answer 8

botulism toxin

Question 9

decreased intestinal fluid absorption through coating of the intestine in a pseudomembrane

Answer 9

clostridium difficile