GI Flashcards
What classification is Reglan?
Antiemetic; GI stimulant
What is the MOA of Reglan?
It accelerates gastric emptying
What are side effects of Reglan?
nausea, diarrhea, drowsiness, dizziness, anxiety
What is Reglan given for?
GERD and management of acute nausea
What is the generic for Reglan?
Metoclopramide
What is the brand name for Omeprazole?
Prilosec
What is the classification of Omeprazole?
antisecretory drug or proton pump inhibitor
What is the indication for Omeprazole?
GERD or duodenal ulcer treatment
Omeprazole’s MOA?
gastric acid pump inhibitor; specifically inhibits ATPase enzyme
What is the generic for Tagamet?
Cimetidine
What is Tagamet’s classification?
histamine H2 antagonist
Tagemet’s MOA?
inhibits the action of histamine at the h2 receptors thereby inhibiting gastric acid secretion
What is Carafate?
An acid protective drug or antiulcer given for doudenal and gastric ulcers.
What is Carafate’s generic?
Sucralfate
What is Flagyl?
An antibiotic given for acute infections
List antihistamines
Dimenhydrinate (Dramamine)
Promethazine (Phenergan)
Meclizine (Antivert)
Hydroxyzine (Vistaril)
List Phenothiazines
Prochlorperazine (Compazine)
Chlorpromazine (Thorazine)
List Histamine 2 (H2) receptor antagonists
Pepcid (Famotidine)
Zantac (Ranitidine)
Tagamet (Cimetidine)
Nizatidine
List Proton pump inhibitors
Prilosec (Omeprazole)
Nexium (Esomeprazole)
Protonix
Prevacid
List Antacids
Maalox
Mylanta
Magnesium hydroxide
Aluminum hydroxide
What is the name of the site of action for vomit-inducing drugs?
Chemoreceptor trigger zone
What is the pylorus?
the region of the stomach that connects to the duodenum (the beginning of the small intestines)
What foods worsen GERD?
caffeine and chocolate
What is pyrosis?
heartburn
Someone with GERD would want to avoid foods high in what?
fat
What is a sliding hernia?
When the stomach slides into thoracic cavity when supine goes back into abdominal cavity when standing upright.
What is a Paraesophageal or rolling hernia?
When the Esophageal junction remains in place, but fundus and greater curvature of stomach roll up through diaphragm
What is a Gastropexy?
Attachment of stomach to diaphragm to prevent re-herniation
What is peptic ulcer disease?
Erosion of GI mucosa resulting from digestive action of HCl acid and pepsin
