geriatrics 2 Flashcards
polypharmacy
the excessive and inappropriate use of medications
adults over __ purchase __% of all prescription medications
65yrs, 30%
older adults are ______ to experience adverse drug reactions (ADR’s)
more likely
___ of older people take at least one unnecessary drug
half
average older adults take at least _ medications
5
average nursing home residents take _ medications
7
characteristics of polypharmacy in older adults
- use of medications for no apparent reason
- use of duplicate medications
- concurrent use of interacting medications
- use of contraindicated drugs
- use of inappropriate dosage
- use of drug therapy to treat adverse drug reactions
Pharmacokinetics of aging, absorption
- decreased gastric acid
- decreased stomach emptying
- decreased gastric motility
Pharmacokinetics of aging, distribution
- decreased body H2O
- increased body fat
- decreased plasma proteins
- decreased lean body mass
Pharmacokinetics of aging, metabolism
- decreased liver mass
- decreased blood flow to liver
- decreased enzyme activity
Pharmacokinetics of aging, excretion
- decreased kidney mass
- decreased blood flow to kidneys
- decreased to nephron function
most commonly overprescribed medications (for older adults)
- laxatives
- BP meds
- diuretics
- diabetes drugs
common side effect of NSAIDs
GI symptoms
common side effect of opiods
sedation
common side effect of antidepressants, analgesics, lithium
confusion
common side effect of barbiturates, antihypertensives
depression
common side effect of antihypertensives
orthostatic hypotension
common side effect of diuretics and glucocorticoids
fatigue/weakness
Prevention of polypharmacy
review pts medication lists
- contraindications?
- dosage?
- pt education?
- do they make sense?
__% of people over age __ reported at least 1 fall in the past year
29%, 65yrs
medical treatment for falls costs more than ___ each year
$50 billion
falls can occur ___ or ___ injury
with or without
____ are the leading cause of hospitalization from injury in older adults
falls
falls are associated with:
- pain
- loss of confidence
- functional decline
- institutionalization
fall risk factors
- prior falls
- fear of falling
- recent hospitalization
- poor sensation
- pain
- difficulty with ADLs
- age over 65
- use of an AD
- impaired balance, gait
- LE weakness
- frailty
- orthostatic hypotension
- polypharmacy
- CVA or neuro diagnosis
- incontinence
- depression or anxiety
- foot problems
- cognitive impairment
- benzodiazepine, diuretics, sedatives
environmental fall risk factors
- slippery/uneven surfaces
- rugs
- poor lighting
- obstacles in path (cords, clutter)
- lack of grab bars or handrails
- poorly arranged furniture
gait speed is correlated with multiple outcomes:
- re-hospitalization
- adl performance
- # of meds
- depressive symptoms
- discharge location from hospital
- history of multiple falls
cut off for community ambulation:
0.8-1.2m/s