Geriatrics Flashcards
What is delirium?
An acute fluctuating syndrome of encephalopathy causing disturbed consciousness, attention, cognition and perception.
What are the 3 subtypes of delirium and how are they defined?
Hypoactive - reduced motor activity, lethargy, withdrawal, drowsiness and staring into space (most common in the elderly)
Hyperactive - increased agitation, delusions and disorientation
Mixed - switching back and forth between hypo and hyperactive states
What are the major risk factors for delirium? (x6)
- age 65+
- male
- pre-existing cognitive deficit e.g. dementia, stroke
- multiple comorbidities
- previous episodes of delirium
- recent surgery
What are some potential causes of delirium? (x5)
- acute infections (e.g. UTI, pneumonia, sepsis)
- prescribed drugs (e.g. benzodiazepines, analgesics, anti-parkinsons meds)
- toxic substances (e.g. alcohol, CO, substance misuse/withdrawal)
- metabolic causes (e.g. hypoxia, electrolyte imbalance, hypoglycaemia)
- surgery - due to problems with cranial bv’s, reduced bp during/after surgery, stress, increased inflammation in body/brain
What are the 8 signs of delirium?
Disordered thinking
Euphoric, fearful or angry
Language impairment
Illusions/delusions/hallucinations
Reversed sleep/wake cycle
Inattention
Unaware/disorientated
Memory impairment
What are the common differentials for delirium diagnosis? (x5)
- dementia
- depression
- bipolar disorder
- functional psychoses e.g. schizophrenia
- thyroid disease
What are the 4 categories of management which must be considered when treating delirium?
- supportive management
- environmemntal measures
- medical management
- management post-discharge
What are some supportive management measures for delirium? (x3)
- clear communication
- reminders of the day, time, location and identification of people
- readily visible clocks and calendars
- familiar objects in surroundings
- staff consistency
What are some environmental measures taken in delirium management? x4
- avoid sensory extremes
- encouragement of normal sleep/wake cycle
- control and maintenance of environment e.g. noise, lighting, temperature
- adequate nutrition
- maintain competence (e.g. walking in ambulant patients)
What are the aims in medical management of delirium? x3
- optimised treatment of comorbidities
- correct underlying precipitants (e.g. treat UTI, constipation etc.)
- only use pharmacological management in select patients who will benefit (e.g. antipsychotics)
What are the diagnostic tools used in assessing patients for delirium?
- CAM (confused assessment method)
- 4AT (4 A’s test = alertness, AMT4, attention, acute change or fluctuating course)
- DSM-5 (diagnostic and statistical manual of mental disorders)
What are the 6 main precipitants of delirium?
Pain
Infection
Nutrition
Co-morbidities
Hydration
Medication
Environment
+ bladder
What is dementia?
not a specific disease but a syndrome defined by memory impairment, some aspects of cognitive decline and difficulties with activities of daily living - it is caused by a number of brain disorders.
What are the 3 groups of symptoms seen in dementia patients?
- cognitive impairment (difficulties with memory, language, attention, orientation etc.)
- psychiatric or behavioural disturbances (changes in personality, emotional control, social behaviour)
- difficulties with ADLs (e.g. driving, shopping, eating, dressing)
What are the 4 main causes of dementia?
- Alzheimer’s disease (≈50%)
- Vascular dementia (≈25%)
- Lewy body dementia (≈15%)
- Fronto-temporal dementia (<5%)
What are some of the causes of potentially treatable dementias? (x5+)
- substance misuse
- hypothyroidism
- space-occupying intracranial lesions
- normal pressure hydrocephalus
- syphilis
- vit B12 deficiency
- folate deficiency
- pellagra (vit B3 deficiency)
What are the diagnostic criteria for all types of dementia?
There are cognitive or behavioural symptoms which:
- affect ability to function in normal activities
- represent a decline from a previous level of function
- cannot be explained by delirium or other major psychiatric disorder
- have been established by history-taking from patient and informant, and formal cognitive assessment
- involve impairment of at least two of the following domains:
- ability to acquire and remember new information
- judgement, ability to reason or handle complex tasks
- visuospatial ability
- language functions
- personality and behaviour
What are some examples of non-pharmacological treatments for dementia? x5
- cognitive stimulation programmes
- music/art/dance therapy
- aromatherapy
- structured exercise programmes
- multisensory stimulation
What are the 2 main groups of medications used in dementia treatment?
- ACE inhibitors e.g. donepezil, galantamine (most used in AD)
- N-methyl-D-aspartate (NMDA) antagonists e.g. ketamine, memantine, dextromethorphan
What are the questions in the 6 CIT test for dementia?
What year is it?
What month is it?
Give an address with 5 parts (John, Smith, 42, High, St, Bedford)
Count 20-1
Say months of year in reverse
Repeat address