Geriatric Pharm things Flashcards by Cristina Resczenski

cardio drugs leading to ADEs

digoxin
thiazide diuretics
B-blocker
diltiazem/verapimil
CCBs
ASA

How well did you know this?

Not at all

Perfectly

conditions: digoxin ADE

w/ impaired renal fxn

How well did you know this?

Not at all

Perfectly

conditions: thiazide diuretic ADEs

w/ Hx of gout

How well did you know this?

Not at all

Perfectly

conditions: B-blocker ADEs

w/ COPD

w/ DM + frequent hyperglycemia

How well did you know this?

Not at all

Perfectly

conditions: diltiazem/verapamil ADEs

w/ class III or IV heart failure

How well did you know this?

Not at all

Perfectly

conditions: CCBs ADEs

w/ chronic constipation

How well did you know this?

Not at all

Perfectly

conditions: dipyridamole ADEs

as monotherapy for cardio secondary prevention

How well did you know this?

Not at all

Perfectly

conditions: ASA ADEs

w/ Hx of PUD w/o H2 antag or PPI
>150 mg
w/o Hx of coronary, cerebral or peripheral vasc sx or occlusive event

How well did you know this?

Not at all

Perfectly

CNS drugs leading to ADEs

TCA
benzos
neuroleptics
antihistamines

How well did you know this?

Not at all

Perfectly

conditions: TCA ADEs

w/ dementia
w/ cardiac conductive abnormalities
w/ constipation
w/ prostatism or hx of urine retention

How well did you know this?

Not at all

Perfectly

conditions: benzos ADEs

long term, long acting

How well did you know this?

Not at all

Perfectly

conditions: neuroleptics ADEs

long term w/ parkinsonism

How well did you know this?

Not at all

Perfectly

conditions: antihis ADEs

prolonged use

How well did you know this?

Not at all

Perfectly

GI drugs causing ADEs

diphenoxylate
loperamide
codeine
PPI

How well did you know this?

Not at all

Perfectly

conditions: diphenoxylate/loperamide/codeine phosphate ADEs

w/ tx of diarrhea w/ unknown cause

for severe infective gastroenteritis

How well did you know this?

Not at all

Perfectly

conditions: PPI ADEs

for PUD @ full dose for >8 wks

How well did you know this?

Not at all

Perfectly

pulm drugs causing ADEs

theophylline

systemic corticosteroids

How well did you know this?

Not at all

Perfectly

conditions: theophylline ADEs

monotherapy for COPD

How well did you know this?

Not at all

Perfectly

conditions: syst corticosteroids ADEs

instead of inhaled for COPD

How well did you know this?

Not at all

Perfectly

conditions: NSAID ADEs

w/ Hx of PUD or GI bleeds (unless w/ H2 ants, PPIs or misoprostol)
w/ mod/severe HTN
w/

How well did you know this?

Not at all

Perfectly

conditions: warfarin ADEs

w/ NSAIDs

How well did you know this?

Not at all

Perfectly

conditions: colchicine ADEs

long term for chronic gout w/o CI to allopurinol

How well did you know this?

Not at all

Perfectly

GU drugs causing ADEs

antimuscarinics

How well did you know this?

Not at all

Perfectly

conditions: antimuscarinic ADEs

for bladder w/ dementia

w/ chronic prostatism

How well did you know this?

Not at all

Perfectly

drugs causing endo ADEs

beta blockers

drugs that cause falls

benzos neuroleptics vasodilators long term opiates

antiemetics: block dopamine

all but ondansatron | promethazine, prochloperazine, metroclopramide

antiemetics: anticholinergics

promethazine | prochloperazine

antiemetics: cholinergics

metroclopramide

antiemetics: 5HT antagonists

ondansatron

antiemetics: alpha blockers

promethazine | prochloperazine

anticholinergics: H1 blockers

``` diphenhydramine hydroxyzine scopolamine dimenhydrinate (promethazine from anti-emetics too) ```

antichol: central

meclizine | dimenhydrinate

antichol: antag 5HT

scopolamine

antichol: blocks Ach

scopolamine, oxybutynin

antichol: M receptor antag

tolterodine | darifenacin (M3)

antichol: inhibit 5HT reuptake

paroxetine | amitriptyline

antichol: down GI motility

diphenoxylate (+ atropine) = lomotil

psych: SSRIs

citalopram sertraline paroxetine

psych: inhibit 5HT, NE and D reuptake

buproprion

psych: 5HT and NE reuptake inhibitor

amitriptyline (CNS) trazodone mirtazapine

psych: up GABA

alprazolam diazepam lorazepam clonazepam

psych: dopamine blocker

haloperidol

psych: block D2 and 5HT

risperidone

anticholinergic class effects

down cognition, hallucinations, sedation, blurry vision, acute glaucoma, tachycardia, dry mouth, urinary retention, constipation, no sweating

DM: stim insulin release

glipizide glyburide repaglinide (sitagliptin too)

DM: up insulin sensitivity

metformin | rosiglitazone

DM: insulin

glargine

DM: inhibit DPP 4

sitagliptin

DM: down glucose absorption

metformin

DM: down hep glucose production

metformin | glargine

DM: slow incretin metab, down glucagon

sitagliptin

HTN: CCBs

amlodipine | diltiazem

HTN: beta blockers

metoprolol

HTN: ACE-Is

lisinopril

HTN: ARBs

losartan

HTN: loops

furosemide

HTN: thiazide

HCTZ

cardio: inhibit vit K

warfarin

cardio: up intracellular Ca

digoxin

cardio: block ADP, prevent aggregation

clopidogrel

cardio: HMG Co-A reductase inhibitors

atorvastatin | simvastatin

GU: alpha 1 blocker

terazosin | tamsulosin

GU: 5 alpha reductase inhibitor

finasteride

GU: m receptor blocker

oxybutynin | tolterodine

GU: beta 3 agonist

mirabegron

alpha agonist

midodine

systemic corticosteroid

prednisolone

osteo: SERM

raloxifene

osteo: bisphosphonates

alendronate risedronate ibandronate

osteo: bind to RANKL

denosumab

Ach-ase inhibitors

donepezil galantamine rivastigmine

NMDA receptor agonists

memantine

pain meds

ibuprofen acetaminophen gabapentin (not really pain but whatever)

H2 blockers

omeprazole

antiemetics: ortho hTN (ADE)

promethazine | prochloperazine

EPS (ADE)

``` promethazine prochloperazine metroclopramide haloperidol risperidone (all D blockers) ```

antiemetics: dizzy (ADE)

promethazine | prochloperazine

antiemetics: torsades

metroclopramide | ondansetron

anticholinergics: tremor (ADE)

paroxetine

antiach: ortho HTN (ADE)

amitriptyline

psych: dizzy

``` SSRIs buproprion trazodone mirtazapine clonazepam ```

psych: ortho HTN

``` amitriptyline trazodone mirtazapine alprazolam haloperidol risperidone ```