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Clinical Medicine > Geriatric Pharm things > Flashcards

Geriatric Pharm things Flashcards

1
Q

cardio drugs leading to ADEs

A 
digoxin
thiazide diuretics
B-blocker
diltiazem/verapimil
CCBs
ASA
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2
Q

conditions: digoxin ADE

A

w/ impaired renal fxn

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3
Q

conditions: thiazide diuretic ADEs

A

w/ Hx of gout

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4
Q

conditions: B-blocker ADEs

A

w/ COPD

w/ DM + frequent hyperglycemia

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5
Q

conditions: diltiazem/verapamil ADEs

A

w/ class III or IV heart failure

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6
Q

conditions: CCBs ADEs

A

w/ chronic constipation

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7
Q

conditions: dipyridamole ADEs

A

as monotherapy for cardio secondary prevention

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8
Q

conditions: ASA ADEs

A

w/ Hx of PUD w/o H2 antag or PPI
>150 mg
w/o Hx of coronary, cerebral or peripheral vasc sx or occlusive event

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9
Q

CNS drugs leading to ADEs

A

TCA
benzos
neuroleptics
antihistamines

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10
Q

conditions: TCA ADEs

A

w/ dementia
w/ cardiac conductive abnormalities
w/ constipation
w/ prostatism or hx of urine retention

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11
Q

conditions: benzos ADEs

A

long term, long acting

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12
Q

conditions: neuroleptics ADEs

A

long term w/ parkinsonism

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13
Q

conditions: antihis ADEs

A

prolonged use

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14
Q

GI drugs causing ADEs

A

diphenoxylate
loperamide
codeine
PPI

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15
Q

conditions: diphenoxylate/loperamide/codeine phosphate ADEs

A

w/ tx of diarrhea w/ unknown cause

for severe infective gastroenteritis

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16
Q

conditions: PPI ADEs

A

for PUD @ full dose for >8 wks

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17
Q

pulm drugs causing ADEs

A

theophylline

systemic corticosteroids

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18
Q

conditions: theophylline ADEs

A

monotherapy for COPD

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19
Q

conditions: syst corticosteroids ADEs

A

instead of inhaled for COPD

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20
Q

conditions: NSAID ADEs

A

w/ Hx of PUD or GI bleeds (unless w/ H2 ants, PPIs or misoprostol)
w/ mod/severe HTN
w/

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21
Q

conditions: warfarin ADEs

A

w/ NSAIDs

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22
Q

conditions: colchicine ADEs

A

long term for chronic gout w/o CI to allopurinol

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23
Q

GU drugs causing ADEs

A

antimuscarinics

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24
Q

conditions: antimuscarinic ADEs

A

for bladder w/ dementia

w/ chronic prostatism

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25
Q

drugs causing endo ADEs

A

beta blockers

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26
Q

drugs that cause falls

A

benzos
neuroleptics
vasodilators
long term opiates

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27
Q

antiemetics: block dopamine

A

all but ondansatron

promethazine, prochloperazine, metroclopramide

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28
Q

antiemetics: anticholinergics

A

promethazine

prochloperazine

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29
Q

antiemetics: cholinergics

A

metroclopramide

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30
Q

antiemetics: 5HT antagonists

A

ondansatron

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31
Q

antiemetics: alpha blockers

A

promethazine

prochloperazine

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32
Q

anticholinergics: H1 blockers

A 
diphenhydramine
hydroxyzine
scopolamine
dimenhydrinate
(promethazine from anti-emetics too)
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33
Q

antichol: central

A

meclizine

dimenhydrinate

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34
Q

antichol: antag 5HT

A

scopolamine

35
Q

antichol: blocks Ach

A

scopolamine, oxybutynin

36
Q

antichol: M receptor antag

A

tolterodine

darifenacin (M3)

37
Q

antichol: inhibit 5HT reuptake

A

paroxetine

amitriptyline

38
Q

antichol: down GI motility

A

diphenoxylate (+ atropine) = lomotil

39
Q

psych: SSRIs

A

citalopram
sertraline
paroxetine

40
Q

psych: inhibit 5HT, NE and D reuptake

A

buproprion

41
Q

psych: 5HT and NE reuptake inhibitor

A

amitriptyline (CNS)
trazodone
mirtazapine

42
Q

psych: up GABA

A

alprazolam
diazepam
lorazepam
clonazepam

43
Q

psych: dopamine blocker

A

haloperidol

44
Q

psych: block D2 and 5HT

A

risperidone

45
Q

anticholinergic class effects

A

down cognition, hallucinations, sedation, blurry vision, acute glaucoma, tachycardia, dry mouth, urinary retention, constipation, no sweating

46
Q

DM: stim insulin release

A

glipizide
glyburide
repaglinide
(sitagliptin too)

47
Q

DM: up insulin sensitivity

A

metformin

rosiglitazone

48
Q

DM: insulin

A

glargine

49
Q

DM: inhibit DPP 4

A

sitagliptin

50
Q

DM: down glucose absorption

A

metformin

51
Q

DM: down hep glucose production

A

metformin

glargine

52
Q

DM: slow incretin metab, down glucagon

A

sitagliptin

53
Q

HTN: CCBs

A

amlodipine

diltiazem

54
Q

HTN: beta blockers

A

metoprolol

55
Q

HTN: ACE-Is

A

lisinopril

56
Q

HTN: ARBs

A

losartan

57
Q

HTN: loops

A

furosemide

58
Q

HTN: thiazide

A

HCTZ

59
Q

cardio: inhibit vit K

A

warfarin

60
Q

cardio: up intracellular Ca

A

digoxin

61
Q

cardio: block ADP, prevent aggregation

A

clopidogrel

62
Q

cardio: HMG Co-A reductase inhibitors

A

atorvastatin

simvastatin

63
Q

GU: alpha 1 blocker

A

terazosin

tamsulosin

64
Q

GU: 5 alpha reductase inhibitor

A

finasteride

65
Q

GU: m receptor blocker

A

oxybutynin

tolterodine

66
Q

GU: beta 3 agonist

A

mirabegron

67
Q

alpha agonist

A

midodine

68
Q

systemic corticosteroid

A

prednisolone

69
Q

osteo: SERM

A

raloxifene

70
Q

osteo: bisphosphonates

A

alendronate
risedronate
ibandronate

71
Q

osteo: bind to RANKL

A

denosumab

72
Q

Ach-ase inhibitors

A

donepezil
galantamine
rivastigmine

73
Q

NMDA receptor agonists

A

memantine

74
Q

pain meds

A

ibuprofen
acetaminophen
gabapentin (not really pain but whatever)

75
Q

H2 blockers

A

omeprazole

76
Q

antiemetics: ortho hTN (ADE)

A

promethazine

prochloperazine

77
Q

EPS (ADE)

A 
promethazine
prochloperazine
metroclopramide
haloperidol
risperidone
(all D blockers)
78
Q

antiemetics: dizzy (ADE)

A

promethazine

prochloperazine

79
Q

antiemetics: torsades

A

metroclopramide

ondansetron

80
Q

anticholinergics: tremor (ADE)

A

paroxetine

81
Q

antiach: ortho HTN (ADE)

A

amitriptyline

82
Q

psych: dizzy

A 
SSRIs
buproprion
trazodone
mirtazapine
clonazepam
83
Q

psych: ortho HTN

A 
amitriptyline
trazodone
mirtazapine
alprazolam
haloperidol
risperidone

Clinical Medicine (9 decks)

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