Genus Moraxella Flashcards

1
Q

Classification

A

Family: Moraxellaceae

Genus: Moraxella

Species:

  • 6 species
  • M.catarrhalis is the most important
    »> formally classified as Neisseria, then more recently, Branhamella

Part of normal oropharyngeal flora
»> now an important opportunistic pathogen

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2
Q

Morphology

A

Gram negative diplococcus

Nonmotile

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3
Q

Virulence factors

A
  • Endotoxin
  • Pili
  • Beta-lactamases
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4
Q

Disease

A

Common

Bronchitis
Bronchopneumonia
Otitis media
Sinusitis

[[[BBOS]]]

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5
Q

Treatment

A

Most strains produce beta-lactamases which destroys penicillins

Reported resistance to: TMP/SMX, clindamycin and tetracycline

Susceptible to: fluoroquinolones, most 2nd & 3rd generation cepholosporins, erythromycin and amoxicillin-clavulanate

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6
Q

Microbiological diagnosis

A

Culture:
Chocolate agar: smooth greyish/white colonies

  • when colonies are pushed with loop, they “scoot” across media

Biochemical tests: oxidase positive

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7
Q

Growth characteristics

A

Aerobic

Fastidious

Oxidase positive

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