Genitourinary FINAL

Question 1

What are the prostate specific Alpha 1 blockers? (3)

Answer 1

Alfuzosin XR (Xatral), Tamsulosin (Flomax), and Silodosin (Rapaflo)

Question 2

Which prostate specific alpha 1 blocker drug can be opened and sprinkled on food?

Answer 2

Silodosin (Rapaflo)

Question 3

What is a combo drug of an A1 blocker and 5- alpha reductase inhibitor?

Answer 3

Jalyn (tamsulosin and dutasteride)

Question 4

What are the 5- alpha reductase inhibitors? (2)

Answer 4

Finasteride (Proscar/ Propecia), and Dutasteride (Avodart)

Question 5

What are the features of A1 blockers in prostate/ how do they work/ what do they do?

Answer 5

-inhibit A1 receptors in prostate gland which relaxes smooth muscle and improves urine flow and incontinence. There is a first dose effect so BP drops with 1st dose

Question 6

What are features of 5-alpha reductase inhibitors/ how they work/ what they do?

Answer 6

Inhibit conversion of testosterone into dihydrotestosterone (DHT) which decreases size of prostate gland and improves urine flow

Question 7

What are the oral systemic estrogen therapy drugs? (1)

Answer 7

Premarin (conjugated estrogens)

Question 7

What are the vaginal local estrogen therapy drugs? (2)

Answer 7

Premarin cream (conjugated estrogens) and Vagifem and Estring (estradiol)

Question 8

What are the anticholinergics used for overactive bladder? (4)

Answer 8

Oxybutynin (Ditropan), Solifenacin (Vesicare), Tolteridone (Detrol), and Fesoterodine (Toviaz)

Question 9

What is the beta-3 adrenergic medication to relax bladder muscle so more urine can be stored?

Answer 9

Mirabegron (Myrbetriq)