genitourinary 2 Flashcards

1
Q

ureteropelvic junction obstruction is

A

congenital disorder that results in hydronephrosis

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2
Q

malignant tumor of ureter

A

urothelial carcinoma

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3
Q

retroperitoneal fibrosis causes

A

obstruction &narrowing of ureter

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4
Q

diverticulum is

A

pouch like evagination of bladder wall

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5
Q

bacterial cystitis is common in

A

women

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6
Q

malakoplakia is

A

defect in phagocytic or degradative function of macrophages leading to undigested bacterial products within phagosomes

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7
Q

michaelis gutmann bodies are

A

deposition of calcium salts

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8
Q

polypoid cystitis is

A

irritation of bladder mucosa forming broad bulbous projection

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9
Q

bladder tumors present with painless

A

hematuria

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10
Q

papillary urothelial carcinoma can invade

A

superficial lamina propria or deep musclaris propria

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11
Q

flat urothelial carcinoma is

A

malignant cells within flat urothelium

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12
Q

adenocarcinomas can arise from

A

urachal remnants

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13
Q

syphilis caused by

A

spirochete, treponema pallidum

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14
Q

syphillis is common in

A

HIV patients

african americans

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15
Q

organism in syphilis can spread through

A

lymphatics and blood even before appearance of skin/mucosal lesion

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16
Q

stages of syphilis

A

primary, secondary, tertiary, congenital

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17
Q

main symptom of primary syphillis

A

chancre

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18
Q

secondary syphilis

A

lymphadenopathy
mucocutaneous lesions
highly infective

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19
Q

tertiary syphilis

A

lesions at distant sites
difficult to find organisms
less likely to be infectious

20
Q

congenital syphilis

A

transplacental transmission

21
Q

gummas are in

A

tertiary syphilis
large areas of parenchymal damage

bones, skin, mucous membranes
lymphocytes, plasma cells, activated macrophages

22
Q

gonorrhea infection requires

A

direct contact with mucosa

23
Q

organisms in gonorrhea attach to

A

mucosal epithelium

24
Q

diagnosis of gonorrhea

A

culture, nucleic acid detection

25
gonorrhea in males
prulent urethral discharge
26
gonorrhea in females
secretions less conspicuous
27
elementary body of c. trachomatis
infectious form, taken up by host by receptor mediated endocytosis
28
reticulate body of c. trachomatis
metabolically active form | uses energy of host cells to replicate &form new elementary bodies
29
lymphogranuloma venereum caused by
c. trachomatis
30
what are lymphogranuloma venereum
nonspecific urethritis or papular or ulcerative lesions involving lower genetalia tender enlarged matted inguinal and/or femoral lymphadenopathy
31
histo of lymphogranuloma venereum
mixed granulomatous & neutrophilic inflammatory response
32
chancroid is
acute, ulcerative infection
33
draining lymph nodes of chancroid may show
necrotizing inflammation --> abscess formation
34
granuloma inguinale caused by
Calymmatobacterium granulomatis
35
donovan bodies are
coccobacilli within vacuoles of macrophages
36
donovan bodies found in
granuloma inguinale
37
incubation of trichomonas vaginalis
4-28 days
38
trichomonas vaginalis in females
asymptomatic/ pruritis, frothy, yellow, vaginal discharge
39
trichomonas vaginalis in males
asymptomatic
40
HSV ___ can cause anogenital/oral infections
1 and 2
41
most anogenital herpes caused by
HSV 2
42
get herpes by
direct contact with mucosal surface/ broken skin
43
herpes virus inactivated by
room temperature
44
cowdry type A inclusion found in
herpes
45
diagnosis of herpes
PCR, viral culture