genitourinary 1 Flashcards

1
Q

in hypospadias urethral orifice is on ___

A

ventral aspect

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2
Q

in epispadias urethral orifice is on

A

dorsal aspect

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3
Q

balanitis is

A

inflammation of glans penis

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4
Q

balanoposthitis is

A

inflammation of overlying prepuce

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5
Q

smegma can lead to

A

phimosis

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6
Q

risk factors of penis tumors

A

poor hygiene, smoking, HPV

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7
Q

condyloma acuminatum is benign or malignant

A

benign

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8
Q

condyloma acuminatum is caused by

A

HPV (mostly 6 and 11)

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9
Q

histo of condyloma acuminatum

A
thickened epidermis (acanthosis) and hyperkeratosis 
koilocytosis
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10
Q

squamous cell carcinoma in situ/ bowen disease benign or malignant

A

malignant

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11
Q

squamous cell carcinoma in situ/ bowen disease caused by

A

high risk HPV (16)

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12
Q

invasive squamous cell carcinoma benign or malignant

A

malignant

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13
Q

invasive squamous cell carcinoma caused by

A

HPV 16 > 18

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14
Q

invasive squamous cell carcinoma looks like

A

papular, crusted, ulcerated lesion on glans or prepuce

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15
Q

hydrocele is

A

accumulation of serous fluid (clear) within tunica vaginalis
scrotal

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16
Q

hematocele is

A

accumulation of blood in tunica vaginalis

scrotal

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17
Q

chylocele is

A

accumulation of lymphatic fluid in tunica vaginalis

scrotal

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18
Q

cryptorchidism is

A

failure of testicular descent into scrotum

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19
Q

crytorchidism leads to increased

A

risk of testicular cancer

and incidence of inguinal hernias

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20
Q

treatment of cryptorchidism

A

orcgiopexy

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21
Q

torsion is

A

twisting of the spermatic cord

obstruction of testicular venous drainage &intense vascular engorgement and infarction

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22
Q

risk factors of testicular neoplasms

A

cryptorchidism

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23
Q

genetics of testicular neoplasms

A

isochromosome 12p

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24
Q

testicular neoplasms arise from

A

germ cell or sex cord stroma

25
germ cell neolasia in situ is found in
parenchyma adjacent to tumor
26
most common pure germ cell tumor is
seminoma
27
tumor markers of seminoma
10% of patients will have increased hCG
28
ovarian counterpart of seminoma
dysgerminoma
29
seminoma looks like
homogenous, lobulated white mass with no hemorrhage or necrosis large uniform cells with distinct cell borders, glycogen rich cytoplasm with lymphocytic infiltrate
30
spermatocytic tumor lacks
lymphocytic infiltrates and granulomas
31
do spermatocytic tumors metastasize
no
32
embryonal carcinoma is more aggressive than
seminoma
33
embryonal carcinoma looks like
invasive masses with hemorrahge and necrosis large tumor cells w/prominent nuclei tubular, alveolar, papillary growth patterns
34
yolk sac tumor is the most common
testicular tumor in children | good prognosis
35
tumor markers of yolk sac tumors
increased AFP levels
36
distinct structure of yolk sac tumor
schiller-duval bodies
37
choriocarcinoma benign or malignant
highly malignant
38
choriocarcinoma tumor cells differentiated into cells resembling
trophoblasts
39
tumor markers of choriocarcinoma
increased hCG
40
ectoderm teratoma is in
neural tissue, skin
41
mesoderm teratoma is in
muscle, cartilage
42
endoderm teratoma is in
thyroid, bronchial epithelium
43
pure teratomas are most common in
infants and kids
44
prepubertal teratomas benign or malignant
benign
45
postpubertal terastomas benign or malignant
malignant and capable of metastasis
46
seminomas remain confined to
testis for long periods | metastasis to iliac and para-aortic lymph nodes
47
nonseminomatous germ cell tumors spread through
lymphatic and hematogenous | liver, lung
48
most hyperplastic lesions in prostate arise in
inner transition zone
49
most carcinomas in prostate arise in
peripheral zones
50
benign prostatic hyperplasia is common cause of
prostatic enlargement caused by proliferation of glandular and stromal elements urinary obstruction
51
DHT is ultimate mediator of
prostatic growth
52
treatment of benign prostatic hyperplasia
agents that inhibit formation of DHT and surgery
53
what is the most common cancer in men
prostatic carcinoma
54
prostatic carcinoma treatment
surgery and radiotherapy, active surveillance for low grade cancers, androgen deprivation for metastatic disease
55
PSA assay is for
prostatic carcinoma
56
cancer is dependent on ___ for survival
androgens
57
squamous cell carcinoma in situ/ bowen disease occurs in
older uncircumsized males
58
squamous cell carcinoma in situ/ bowen disease appears grossly as
solitary plaque on the shaft of the penis.