Genital Lumps Flashcards
What is a papule?
A lesion usually <0.5 cm
What is a plaque?
A plate-like lesion usually >0.5 cm
What is a wheal?
An oedematous papule or plaque with surrounding erythema (flare)
What is a nodule?
A deep solid lesion usually >0.5 cm
What is a papilloma?
A rounded epithelial mass. Papillomas may be pedunculated (on a stalk). Papillomas due to human papillomavirus may have a cauliflower appearance or feel gritty
What is a cyst?
A closed, lined cavity filled with fluid or semi-solid material
What is a vesicle?
A blister <0.5 cm
What is a bulla?
A blister >0.5 cm
What is a pustule?
A small erythematous elevation with central pus
What is an abscess?
A localised deep collection of pus
What is a furuncle?
A follicle-centred erythematous nodule +/- pus
What is a macule?
A flat lesion <0.5 cm
What is a patch?
A flat lesion >0.5 cm
What are 5 normal variants accounting for genital lumps?
- Pearly penile papules
- Parafrenular glands
- Fordyce spots
- Vestibular papillae
- Nabothian follicles
What are vestibular papillae?
Rare, usually small, frond-like glands
The appearance is small, smooth projections that look like cobblestones
Unlike warts, vestibular papillae are usually symmetrically placed, but in some patients, the distinction between early, soft genital warts and vestibular papillae can be difficult. In these cases, the management is review in 1-2 months.
What are parafrenular glands?
Distinction from warts is usually made by palpation - the glands are typically small, smooth and symmetrical in comparison to warts, which have a rough surface
What is the incubation period for MC?
3-12 weeks
Which strains of HPV account for GW?
6 and 11 (accounts for 90%)
How is HPV acquired?
HPV infects epithelial cells of the skin and mucosa – entry is thought to occur through microabrasions eg, those associated with sexual intercourse
How should warts be followed-up if they have prev. responded to treatment?
Patients whose original lesions have responded well to treatment but in whom new lesions are developing, can continue with the current regimen.
When should an agent treating warts be changed?
The patient is not tolerating current treatment
There is under 50% response to current treatment by six weeks (8-12 weeks for imiquimod)