Genital embryology Flashcards
Female
default development:
Mesonephric degenerates
Paramesonephric develops
Male
SRY on Y chromosome; produces testis-determining factor (testes development), which develop testes
Sertoli cells secrete Mullerian inhibitory factor MIF, which suppresses development of paramesonephric duct
Leydigs secretes androgens that stimulate the development of mesonephric ducts.
Paramesonephric (Mullerian) duct
Female internal structures:
fallopian tube,
uterus,
upper portion of vagina (vs. lower from urogenital sinus)
Mullerian duct abnormalities
Anatomical defects that present as
primary amenorrhea in females with fully developed sexual characteristics (which indicate functional ovaries)
Mesonephric (Wolffian) duct
Male internal structures (except prostate): Seminal vesicles, Epididymus, Ejaculatory duct, Ductus deferens
SEED
Bicornuate uterus
From incomplete fusion of paramesonephric duct;
can lead to urinary tract abn and miscarriages.