Genes of embryogenesis Flashcards
1
Q
Shh
A
Limb base in the zone of polarizing activity
Pattern along AP axis
CNS development
(mutation=holoprosencephaly)
2
Q
Wnt7
A
Apical ectodermal ridge
(distal end of each developing lib)
Pattern along DV axis (vs. SHH)
3
Q
FGF
A
Apical ectodermal ridge
Stimulates mitosis of underlying mesoderm.
Lengthening of limbs
4
Q
Hox
A
Segmental organization of embryos in craniocaudal direction.
Mutation = appendages in wrong locations