Genetics Quiz Questions Flashcards
T/F The genetic information needed for protein synthesis is encoded in the DNA contained in the cell nucleus.
True
T/F Polygenic inheritance can be predicted utilizing the Mendelian laws of genetic transmission.
False- single gene disorders
T/F Messenger RNA carries the instructions for protein synthesis
True
T/F The genotype refers to the recognizable traits, physical or biochemical, associated with a specific phenotype.
False- The PHENOTYPE refers to the recognizable traits, physical or biochemical, associated with a specific GENOTYPE
T/F The Punnett square can be utilized to describe possible combinations that can occur with transmission of single-gene dominant and recessive traits.
True
T/F Ribosomal is the type of RNA that functions to deliver the activated form of amino acids to protein molecules in the ribosomes.
False- tRNA
T/F Autosomal recessive disorders are manifested even if only one member of the gene pair is affected.
False- Autosomal DOMINANT disorders
T/F A teratogenic agent is an environmental agent that produces abnormalities only during the first 4 weeks of embryonic or fetal development
False - 15-50 days
T/F Down syndrome, Turner syndrome and Klinefelter syndrome are all examples of chromosomal disorders that occur from an alteration in chromosome number.
True
T/F Sex-linked disorders almost always are associated with the X chromosome and are predominantly recessive.
True
Which of the following statements about CF is correct?
- CF is an autosomal dominant trait
- CF results from a mutation in the CFTR gene, which normally encodes a chloride ion channel
- the most common mutation associated with CF is a single nucleotide polymorphism (point mutation) in the CFTR gene
- Normally individuals with a mutation in the CFTR have a normal sweat test
A person with cystic fibrosis may be at risk of bleeding due to:
- Excessive fat digestion
- Decreased vitamin K absorption
- Compromised chloride ion transport
- Increased secretions throughout the gut
A person with CF may have decrased fertility
T/F
True
Two parents with the trait for sickle cell disease (so they are heterozygotes) have a child. What is the risk of that child having sickle cell disease?
- 0%
- 25%
- 50%
- 100%
Many of the s/s of SCD (hyperbillirubinema, decreased hematocrit, enlarged liver and spleen) are due to excessive hemolysis experienced by individuals with SCD
True
Sickle cell disease is an autosomal recessive disease that is caused by a point mutation in the beta globin gene.
T/F
True
Risk of Down Syndrome may be associated with which of the following?
- Advanced maternal age
- Previous child with down syndrome
- being a carrier of a genetic translocation for Down syndrome
- All of the above may occur in a child with Downs
All of the above
Which of the following complications may be evident in a child with Down Syndrome?
- Heart Defects
- Hearing Loss
- Poor Vision
- All of the above
All of the above
Parents of a Down syndrome child are typically genetically normal (have a normal karyotype)
T/F
True
Hemophilia is an example of which type of inheritance?
X-linked recessive
If Bob has an inherited form of hemophillia, most likely his father would be:
- a hemophilliac (affected)
- a carrier
- unaffected without an affected allele
- it is not possible to know about bob’s father with regard to his hemophilla status
It is not possible to know
Hemophillia may be acquired rather than genetic, a form of the disease that involves development of autoantibodies against clotting factors (Factor VIII)
T/F
True
