Cancer Quiz Questions

Question 1

T/F Cancer is a disorder of altered cell differentiation and growth.

Answer 1

True

Question 2

T/F Surgery, radiation, and chemotherapy are the only identified treatment modalities for cancer.

Answer 2

False- also includes hormonal therapy and biotherapy

Question 3

T/F The Papanicolaou test is a cytologic method used to detect cancer cells.

Answer 3

True

Question 4

T/F Cell differentiation is the process whereby proliferating cells are transformed into different and more specialized cell types.

Answer 4

True

Question 5

T/F Benign neoplasms are less differentiated tumors that grow in a crab-like manner to invade surrounding tissues, have cells that break loose and travel to distant sites to form metastases, and inevitably cause suffering and death unless their growth can be controlled through treatment.

Answer 5

False- Malignant Neoplams

Question 6

T/F DNA synthesis takes place during the G0 phase of the cell cycle.

Answer 6

False- S phase

Question 7

T/F The process of grading a tumor involves the microscopic examination of cancer cells to determine their level of differentiation and the number of mitoses.

Answer 7

True

Question 8

T/F In general, benign tumors usually are named by adding the suffix “—oma” to the parenchymal tissue type from which the growth originated.

Answer 8

True

Question 9

T/F The term invasion is used to describe the development of a secondary tumor in a location distant from the primary tumor.

Answer 9

False- Metastasis

Question 10

T/F Hematogenic spread would involve metastasis that occurs by way of the blood vessels.

Answer 10

True

Question 11

Which of the following test is MOST LIKELY considered diagnostic for colon cancer?

• colonoscopy
• FOBT
• CEA
• biopsy

Answer 11

colonoscopy??

Question 12

The pathology report indicated no involvement of the lymph nodes. Thus, it is likely that treatment would include chemotherapy after surgical removal of the tumor, since metastasis has likely already occured. T/F

Answer 12

False

Question 13

The mutation associated with retinoblastoma is expressed in which of the following proteins?

• p53
• pRB
• BRCA1
• DCC

Answer 13

pRB

Question 14

For retinoblastoma, a germline mutation would most likely give rise to bilateral involvement before about 2 years of age. T/F

Answer 14

False– 5 years old

Question 15

Which of the following exposures provide an increased risk of lung cancer?

• Cigarette smoking
• Second-hand smoking
• Pollution
• all of the above

Answer 15

???All of the above

Question 16

Lung cancer is a classic example of the initiation-promotion-progression theory of carcinogenesis. According to this theory, which of teh following statements is correct?
-Iniiation is a reversible step caused by exposure to ciarette smoke
=Promotion is initially reversible, but if it occurs after initiation tumors may form
-Progression is an irreversible step that involves the mutation of DNA within the cell
-Promotion is associated with metastasis and chromosomal instability among other cellular changes

Answer 16

B????

Question 17

Oat cell carcinoma is a type of lung cancer that may be associated with SIADH since these tumor cells may release ADH. T/F

Answer 17

True

Question 18

Chronic myeloid leukemia (CML) may be associated with which of the following genetic changes?

• a point mutation in a tyrosine kinase
• a translocation between two chromosomes
• the loss of a whole chromosome
• the inversion of one complete arm of chromosome

Answer 18

B???

Question 19

which of the following tests can be used to detect the genetic change associated with CML?

• Karyotype
• Fluorescence in situ hybridization (FISH)
• Polymerase chain reaction (PCR)
• All of the above

Answer 19

??? D?

Question 20

The result of the genetic change associated with CML is activation of a tyrosine kinase

Answer 20

True