Genetics (paper1) Flashcards
What does DNA stand for
Deoxyribonucleic acid
What does DNA contain
Instructions for making the cell, producing proteins
What is a gene
A piece or length of DNA giving instructions for a protein e.g. To make insulin.
Describe the structure of DNA
Made of 2 strands
Sides are made of a sugar-deoxyribose and phosphate
What are the 4 genes in DNA
Guanine, cytosine, adenine and thymine
What are they held together by
Complementary base pairs are held together by a weak hydrogen bond
What was the structure of DNA known
1953
Name some key players in DNA discovery
Rosalind Franklin and James Watson
What do genes code for
Proteins
What are proteins made up of
Amino acids
Where does protein synthesis happen
In the ribosomes
Explain step one of protein synthesis
The coding strand is copied
This is known as transcription
DNA acts as a template to make mRNA
What is RNA
Ribonucleic acid
What is different with RNA to DNA
It has 1 strand and contains Uracil instead of thymine
Explain step 2 of protein synthesis
mRNA leaves the nucleus via the pores and travels to the ribosomes
mRNA code is read- this is known as translation
This gives the order of amino acids
How many amino acids are there
21
What happens in translation
tRNA carries the amino acids to the ribosomes
The ribosome links together the amino acids to make a polypeptide
What do multiple amino acids make
Polypeptide
What is a mutation
A change in DNA base sequence such as addition, deletion or substitution
What can a mutation change
The mRNA sequence and the amino acid used or the order